Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | MASP2 | O00187 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1124438 | 0.87 | PTGS2 (0.55) | PTGS2HDAC1HDAC4TSHRLMNA | |
| SCHEMBL1124437 | 0.87 | PTGS2 (0.55) | PTGS2HDAC1HDAC4TSHRLMNA | |
| SCHEMBL1233338 | 0.86 | HDAC1 (0.54) | MASP2F2HDAC1LMNAMAPT | |
| SCHEMBL1399154 | 0.86 | HDAC1 (0.54) | MASP2F2HDAC1LMNAMAPT | |
| SCHEMBL11853194 | 0.80 | POLB (0.50) | MASP2F2HDAC1HDAC4LMNA | |
| SCHEMBL11853199 | 0.80 | POLB (0.50) | MASP2F2HDAC1HDAC4LMNA | |
| SCHEMBL13004933 | 0.77 | NFKB1 (0.53) | MASP2F2HDAC1HDAC4MAPT | |
| SCHEMBL13004328 | 0.77 | NFKB1 (0.53) | MASP2F2HDAC1HDAC4MAPT | |
| SCHEMBL17866914 | 0.77 | NFKB1 (0.53) | MASP2F2HDAC1HDAC4MAPT | |
| SCHEMBL17866912 | 0.77 | NFKB1 (0.53) | MASP2F2HDAC1HDAC4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973877-A2 | CANNIBINOID RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007084450-A2 | CANNIBINOID RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2007-07-26 | — | — | WO | disclosed |