SCHEMBL9852877

SCHEMBL9852877

O=[C]CC(c1ccccc1)c1cccc2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.54
ALDH1A1 P00352 3/20 0.45
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP1A2 P05177 1/20 0.44
ACP3 P15309 3/20 0.42
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.41
TSHR P16473 1/20 0.37
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
ADRA1D P25100 1/20 0.36
ADRA1A P35348 1/20 0.36
ADRA1B P35368 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8470103 0.91 CYP2C9 (0.48) SLC6A4ALDH1A1CYP2C9CYP2C19CYP1A2
SCHEMBL9853050 0.79 SLC6A4 (0.54) SLC6A4ALDH1A1CYP2C9CYP2C19CYP1A2
SCHEMBL12506240 0.78 SLC6A4 (0.65) SLC6A4ALDH1A1CYP2C9CYP2C19CYP1A2
SCHEMBL3744199 0.77 ALDH1A1 (0.46) SLC6A4ALDH1A1CYP2C9CYP2C19CYP1A2
SCHEMBL833319 0.77 HTR2A (0.46) ALDH1A1TSHR
SCHEMBL5010133 0.77 SLC6A4 (0.58) SLC6A4ALDH1A1CYP2C9CYP2C19CYP1A2
SCHEMBL613009 0.77 SLC6A4 (0.58) SLC6A4ALDH1A1CYP2C9CYP2C19CYP1A2
SCHEMBL28326874 0.76 CYP2C9 (0.59) SLC6A4ALDH1A1CYP2C9CYP2C19CYP1A2
SCHEMBL6006319 0.74 SLC6A4 (0.64) SLC6A4ALDH1A1CYP2C9CYP2C19CYP1A2
SCHEMBL16721029 0.74 SLC6A4 (0.64) SLC6A4ALDH1A1CYP2C9CYP2C19CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0441226-A1 (cyanomethyl)pyridines useful as PAF antagonists J. URIACH & CIA. S.A. (ES) 1991-08-14 EP disclosed