Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10771644 | 0.83 | ESR1 (0.43) | KIF11CYP2C19CYP1A2CYP2D6HSD17B10 | |
| SCHEMBL16721031 | 0.82 | CYP2C19 (0.44) | KIF11CYP2C19CYP1A2CYP2D6HSD17B10 | |
| SCHEMBL5010732 | 0.80 | ACP3 (0.42) | KIF11CYP2C19CYP1A2CYP2D6HSD17B10 | |
| SCHEMBL6547735 | 0.76 | ALDH1A1 (0.43) | CYP2C19CYP1A2CYP2D6HSD17B10CYP2C9 | |
| SCHEMBL2127614 | 0.76 | ALDH1A1 (0.43) | CYP2C19CYP1A2CYP2D6HSD17B10CYP2C9 | |
| SCHEMBL7217419 | 0.76 | KIF11 (0.41) | KIF11CYP2C19CYP1A2CYP2D6HSD17B10 | |
| SCHEMBL30084848 | 0.76 | KIF11 (0.47) | KIF11CYP2C19CYP1A2CYP2D6HSD17B10 | |
| SCHEMBL8804043 | 0.76 | KIF11 (0.38) | KIF11CYP2C19CYP1A2CYP2D6HSD17B10 | |
| SCHEMBL7907348 | 0.76 | ALDH1A1 (0.39) | KIF11CYP2C19CYP1A2CYP2D6HSD17B10 | |
| SCHEMBL14315573 | 0.75 | KIF11 (0.43) | KIF11CYP2C19CYP1A2CYP2D6HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |