Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | TYR | P14679 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5013814 | 0.76 | ESR1 (0.40) | SRCTYRMAPTPTGS2KDM4E | |
| SCHEMBL3453786 | 0.76 | ESR1 (0.40) | SRCTYRMAPTPTGS2KDM4E | |
| SCHEMBL5010801 | 0.75 | SRC (0.42) | SRCSTSALOX15TYRMEN1 | |
| SCHEMBL16981555 | 0.67 | CYP1A2 (0.45) | ALOX15TP53CYP3A4PTGS2KDM4E | |
| SCHEMBL16981552 | 0.67 | CYP1A2 (0.45) | ALOX15TP53CYP3A4PTGS2KDM4E | |
| SCHEMBL13564086 | 0.67 | CYP1A2 (0.45) | ALOX15TP53CYP3A4PTGS2KDM4E | |
| SCHEMBL14092904 | 0.66 | CNR1 (0.33) | SRCLTB4RALOX5PTGS2KDM4E | |
| SCHEMBL13564005 | 0.65 | CYP1A2 (0.46) | ALOX15TP53CYP3A4PTGS2KDM4E | |
| SCHEMBL14340029 | 0.65 | HSD17B10 (0.52) | MEN1KMT2ATP53CYP3A4MAPT | |
| SCHEMBL5483456 | 0.65 | HSD17B10 (0.52) | MEN1KMT2ATP53CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |