SCHEMBL5010236

SCHEMBL5010236

COc1nccnc1-c1ccc(F)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 9/20 0.45
SQOR Q9Y6N5 3/20 0.43
MAPK13 O15264 4/20 0.42
MAPK12 P53778 4/20 0.42
MAPK11 Q15759 4/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
KMT2A Q03164 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
ALOX5 P09917 1/20 0.42
GCGR P47871 1/20 0.42
RAF1 P04049 1/20 0.41
MAPK9 P45984 1/20 0.41
PDE10A Q9Y233 1/20 0.41
GRIA1 P42261 1/20 0.41
MAPK10 P53779 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5005954 0.80 NPC1 (0.50) SQORKDM4EMEN1CYP1A2KMT2A
SCHEMBL4148219 0.79 PDE3B (0.47) MAPK14MAPK13MAPK12MAPK11GCGR
SCHEMBL23205944 0.76 KIT (0.52) KDM4EMEN1CYP3A4KMT2APDE10A
SCHEMBL22613006 0.76 APLNR (0.36) KDM4EMEN1CYP1A2KMT2A
SCHEMBL15674490 0.76 SYK (0.49) MAPK14SQORKDM4EMEN1KMT2A
SCHEMBL6337863 0.75 MAPK14 (0.60) MAPK14MAPK13MAPK12MAPK11GCGR
SCHEMBL5010264 0.75 PDGFRB (0.41) MAPK14SQORMEN1CYP1A2CYP3A4
SCHEMBL2040773 0.75 FFAR2 (0.47) KDM4EMEN1CYP1A2KMT2A
SCHEMBL29788291 0.75 FFAR2 (0.47) KDM4EMEN1CYP1A2KMT2A
SCHEMBL29501268 0.74 NPC1 (0.56) SQORKDM4EMEN1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8541574-B2 Organometallic complex, and light-emitting element, light-emitting device and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-09-24 US disclosed
US-8541574-B2 Organometallic complex, and light-emitting element, light-emitting device and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-09-24 US disclosed
US-8541574-B2 Organometallic complex, and light-emitting element, light-emitting device and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-09-24 US disclosed
US-20130079516-A1 Organometallic Complex, and Light-Emitting Element, Light-Emitting Device and Electronic Device Using the Organometallic Complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-28 US disclosed
US-20130079516-A1 Organometallic Complex, and Light-Emitting Element, Light-Emitting Device and Electronic Device Using the Organometallic Complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-28 US disclosed
US-20130079516-A1 Organometallic Complex, and Light-Emitting Element, Light-Emitting Device and Electronic Device Using the Organometallic Complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-03-28 US disclosed
US-20080312437-A1 Organometallic Complex, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Organometallic Complex SEMICONDUCTOR ENERGY LABRATORY CO., LTD. 2008-12-18 US disclosed
US-20080312437-A1 Organometallic Complex, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Organometallic Complex SEMICONDUCTOR ENERGY LABRATORY CO., LTD. 2008-12-18 US disclosed
US-20080312437-A1 Organometallic Complex, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Organometallic Complex SEMICONDUCTOR ENERGY LABRATORY CO., LTD. 2008-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080312437-A1 Organometallic Complex, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Organometallic Complex NR2E3, AP2M1, AP3M1 MAPK14 4727/4885SQOR 384/4885MAPK13 4760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.