Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703097 | 0.75 | — | — | |
| Methylamine SCHEMBL22022513 | 0.73 | FDPS (0.32) | ALDH1A1 | |
| SCHEMBL5008285 | 0.71 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL705105 | 0.69 | — | — | |
| SCHEMBL5005027 | 0.68 | — | — | |
| SCHEMBL10561552 | 0.68 | — | — | |
| SCHEMBL1035795 | 0.67 | — | — | |
| SCHEMBL31293625 | 0.66 | — | — | |
| SCHEMBL613324 | 0.66 | — | — | |
| SCHEMBL29201684 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306182-A1 | Reactive filler for dental cements | BRUGGER STEFAN | 2008-12-11 | — | — | US | claimed |
| EP-1789008-A1 | REACTIVE FILLER FOR DENTAL CEMENTS | DENTSPLY DETREY GmbH (DE) | 2007-05-30 | — | — | EP | claimed |
| US-20060160919-A1 | Reactive filler for dental cements | DENTSPLY DE TREY GMBH (DE) | 2006-07-20 | — | — | US | claimed |
| EP-1634561-A1 | Reactive filler for dental cements | DENTSPLY DETREY GmbH (DE) | 2006-03-15 | — | — | EP | claimed |
| WO-2006013111-A1 | REACTIVE FILLER FOR DENTAL CEMENTS | DENTSPLY DETREY GMBH (DE) | 2006-02-09 | — | — | WO | claimed |
| US-20230140993-A1 | ORGANOPOLYSILOXANE AND CURABLE COMPOSITION CONTAINING SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-05-11 | — | — | US | disclosed |
| EP-4122939-A1 | ORGAOPOLYSILOXANE AND CURABLE COMPOSITION CONTAINING SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-01-25 | — | — | EP | disclosed |
| EP-3984516-A1 | COMPOSITE FILLER PARTICLES AND PROCESS FOR THE PREPARATION THEREOF | Dentsply DeTrey GmbH (DE) | 2022-04-20 | — | — | EP | disclosed |
| US-10040969-B2 | Composite filler particles and process for the preparation thereof | DENTSPLY SIRONA INC. (US) | 2018-08-07 | — | — | US | disclosed |
| US-20160024334-A1 | COMPOSITE FILLER PARTICLES AND PROCESS FOR THE PREPARATION THEREOF | DENTSPLY INTERNATIONAL INC. (US) | 2016-01-28 | — | — | US | disclosed |
| US-9193849-B2 | Composite filler particles and process for the preparation thereof | DENTSPLY INTERNATIONAL INC. (US) | 2015-11-24 | — | — | US | disclosed |
| US-20130158157-A1 | COMPOSITE FILLER PARTICLES AND PROCESS FOR THE PREPARATION THEREOF | DENTSPLY INTERNATIONAL INC. (US) | 2013-06-20 | — | — | US | disclosed |
| EP-2604247-A1 | Composite filler particles and process for the preparation thereof | Dentsply DeTrey GmbH (DE) | 2013-06-19 | — | — | EP | disclosed |
| US-20080306182-A1 | Reactive filler for dental cements | BRUGGER STEFAN | 2008-12-11 | — | — | US | disclosed |
| EP-1789008-A1 | REACTIVE FILLER FOR DENTAL CEMENTS | DENTSPLY DETREY GmbH (DE) | 2007-05-30 | — | — | EP | disclosed |
| US-20060160919-A1 | Reactive filler for dental cements | DENTSPLY DE TREY GMBH (DE) | 2006-07-20 | — | — | US | disclosed |
| EP-1634561-A1 | Reactive filler for dental cements | DENTSPLY DETREY GmbH (DE) | 2006-03-15 | — | — | EP | disclosed |
| WO-2006013111-A1 | REACTIVE FILLER FOR DENTAL CEMENTS | DENTSPLY DETREY GMBH (DE) | 2006-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306182-A1 | Reactive filler for dental cements | CD44, L1CAM, ITGAM | ALDH1A1 1833/4885 |
| US-10040969-B2 | Composite filler particles and process for the preparation thereof | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, C9, H1-10 | ALDH1A1 2176/4885 |
| US-20060160919-A1 | Reactive filler for dental cements | CD44, L1CAM, ITGAM | ALDH1A1 1788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.