SCHEMBL501046

SCHEMBL501046

O=C(O)CCCN1C(=O)CCC1=O

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 4/20 0.50
PTGS2 P35354 4/20 0.50
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
GAA P10253 2/20 0.49
SMN1; SMN2 Q16637 4/20 0.46
ALDH1A1 P00352 3/20 0.46
MAPT P10636 1/20 0.46
CYP1A2 P05177 1/20 0.45
MAPK1 P28482 1/20 0.45
HPGD P15428 1/20 0.44
HTT P42858 1/20 0.44
HSD17B10 Q99714 2/20 0.44
CASP1 P29466 1/20 0.44
SLC22A6 Q4U2R8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL5092840 0.94 PTGS1 (0.46) PTGS1PTGS2MEN1KMT2AGAA
SCHEMBL7463384 0.94 PTGS1 (0.58) PTGS1PTGS2MEN1KMT2AGAA
SCHEMBL27248010 0.92 PTGS1 (0.61) PTGS1PTGS2MEN1KMT2AGAA
SCHEMBL5698008 0.92 PTGS1 (0.61) PTGS1PTGS2MEN1KMT2AGAA
SCHEMBL9410394 0.92 PTGS1 (0.61) PTGS1PTGS2MEN1KMT2AGAA
SCHEMBL5697933 0.92 PTGS1 (0.61) PTGS1PTGS2MEN1KMT2AGAA
SCHEMBL1618771 0.92 PTGS1 (0.61) PTGS1PTGS2MEN1KMT2AGAA
SCHEMBL7259687 0.92 PTGS1 (0.61) PTGS1PTGS2MEN1KMT2AGAA
SCHEMBL5698003 0.92 PTGS1 (0.61) PTGS1PTGS2MEN1KMT2AGAA
SCHEMBL11009569 0.92 PTGS1 (0.61) PTGS1PTGS2MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3689898-B1 LONG-ACTING CONJUGATE OF GLUCAGON-LIKE PEPTIDE-2 (GLP-2) DERIVATIVE HANMI PHARMACEUTICAL CO LTD (KR) 2026-04-29 EP claimed
EP-2963055-B1 SITE-SPECIFIC INSULIN CONJUGATE HANMI PHARM IND CO LTD (KR) 2019-05-15 EP claimed
EP-2799539-B1 HUMAN ARGINASE AND FIXED-POINT PEGYLATED HUMAN ARGINASE AND USE THEREOF BIO-CANCER TREAT INT LTD (SHANGHAI) (CN) 2017-09-13 EP claimed
EP-1646661-B1 LIVING RADICAL POLYMERIZATION INITIATOR COMPRISING A FUNCTIONAL GROUP CAPABLE OF REACTING WITH POLYPEPTIDES OR THE LIKE, COMB POLYMER OBTAINED THEREWITH, POLYPEPTIDE CONJUGATES AND DRUNG OBTAINED THEREFROM WARWICK EFFECT POLYMERS LTD (GB) 2009-04-01 EP claimed
EP-1476489-B8 HYDROLYTICALLY DEGRADABLE ALKYLENE OXIDE BASED POLYMERS NEKTAR THERAPEUTICS AL CORP (US) 2008-10-08 EP claimed
EP-1345982-B1 SYNTHESIS OF HIGH MOLECULAR WEIGHT NON-PEPTIDIC POLYMER DERIVATIVES NEKTAR THERAPEUTICS AL CORP (US) 2007-04-25 EP claimed
US-20060239961-A1 Hydrolytically degradable alkylene oxide based polymers NEKTAR THERAPEUTICS AL, CORPORATION (US) 2006-10-26 US claimed
EP-1476489-A1 HYDROLYTICALLY DEGRADABLE ALKYLENE OXIDE BASED POLYMERS Nektar Therapeutics Al, Corporation (US) 2004-11-17 EP claimed
WO-2003070805-A1 HYDROLYTICALLY DEGRADABLE ALKYLENE OXIDE BASED POLYMERS NEKTAR THERAPEUTICS AL, CORPORATION (US) 2003-08-28 WO claimed
US-20030023023-A1 Hydrolytically degradable polymers and hydrogels made therefrom SHEARWATER CORPORATION 2003-01-30 US claimed
US-6348558-B1 OLIGOMERS COMPRISING ALKYLENE OXIDE MONOMERS AND CARBONATE LINKAGES; POLYCARBONATEETHER COPOLYMERS; DRUG DELIVERY; CONJUGATED TO PEPTIDES OR PROTEINS FOR REDUCED IMMUNOGENICITY; STABILITY SHEARWATER CORPORATION 2002-02-19 US claimed
EP-0366041-B2 Imido-percarboxylic acids AUSIMONT SPA (IT) 2001-09-12 EP claimed
EP-0366041-B1 Imido-percarboxylic acids AUSIMONT SPA (IT) 1998-08-05 EP claimed
EP-0366041-A2 Imido-percarboxylic acids AUSIMONT S.r.l. (IT) 1990-05-02 EP claimed
US-20250388934-A1 PROTEIN HAVING NUCLEASE ACTIVITY, FUSION PROTEINS AND USES THEREOF HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM GESUNDHEIT & UMWELT GMBH (DE) 2025-12-25 US disclosed
WO-2025233381-A1 ENZYMES THAT ELIMINATE PYRIMIDINE AND/OR PURINE NUCLEOSIDES FOR TREATING CANCER Technische Universität München, in Vertretung des Freistaates Bayern (DE) 2025-11-13 WO disclosed
EP-4554677-A1 BINDING MOLECULES FOR THE TREATMENT OF CANCER Boehringer Ingelheim International GmbH (DE) 2025-05-21 EP disclosed
EP-0366041-B1 Imido-percarboxylic acids AUSIMONT SPA (IT) 1998-08-05 EP disclosed
US-5536434-A BLEACHES AUSIMONT S.P.A. (IT) 1996-07-16 US disclosed
EP-0366041-A2 Imido-percarboxylic acids AUSIMONT S.r.l. (IT) 1990-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060239961-A1 Hydrolytically degradable alkylene oxide based polymers HAO2, IDE, APEH PTGS1 411/4885PTGS2 264/4885MEN1 3777/4885
US-20250388934-A1 PROTEIN HAVING NUCLEASE ACTIVITY, FUSION PROTEINS AND USES THEREOF DNASE1, DNASE1L3, NUDT21 PTGS1 3647/4885PTGS2 3835/4885MEN1 2074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.