Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.81 |
| ▸ | HTR2C | P28335 | 1/20 | 0.81 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.81 |
| ▸ | CNR2 | P34972 | 5/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5011454 | 0.91 | HTR2A (0.77) | HTR2AHTR2CSLC6A4CNR2TP53 | |
| SCHEMBL5011732 | 0.90 | HTR2A (1.00) | HTR2AHTR2CSLC6A4CNR2TP53 | |
| SCHEMBL5010582 | 0.87 | CNR2 (0.71) | HTR2AHTR2CSLC6A4CNR2TP53 | |
| SCHEMBL5010683 | 0.86 | HTR2A (0.70) | HTR2AHTR2CSLC6A4CNR2TP53 | |
| SCHEMBL5011430 | 0.86 | HTR2A (0.70) | HTR2AHTR2CSLC6A4CNR2TP53 | |
| SCHEMBL5009431 | 0.85 | CNR2 (0.73) | HTR2AHTR2CSLC6A4CNR2TP53 | |
| SCHEMBL13911246 | 0.85 | GAA (0.67) | HTR2AHTR2CSLC6A4CNR2MEN1 | |
| SCHEMBL984791 | 0.84 | TAS2R14 (0.71) | CNR2MEN1KMT2ATAS2R14MAPT | |
| SCHEMBL5011405 | 0.84 | HTR2A (0.70) | HTR2AHTR2CSLC6A4CNR2TP53 | |
| SCHEMBL15677741 | 0.82 | RXFP1 (0.63) | HTR2AHTR2CSLC6A4CNR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093919-A1 | USE OF N-BENZYL-N-(2-DIMETHYLAMINO-ETHYL)BENZENESULFONAMIDE DERIVATIVES FOR TREATING CENTRAL NERVOUS SYSTEM DISORDERS | DONGBU HITEK CO., LTD. (KR) | 2008-08-07 | — | — | WO | claimed |
| WO-2008093919-A1 | USE OF N-BENZYL-N-(2-DIMETHYLAMINO-ETHYL)BENZENESULFONAMIDE DERIVATIVES FOR TREATING CENTRAL NERVOUS SYSTEM DISORDERS | DONGBU HITEK CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |
| WO-2008093919-A1 | USE OF N-BENZYL-N-(2-DIMETHYLAMINO-ETHYL)BENZENESULFONAMIDE DERIVATIVES FOR TREATING CENTRAL NERVOUS SYSTEM DISORDERS | DONGBU HITEK CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |