SCHEMBL984791

SCHEMBL984791

O=S(=O)(c1ccccc1)N(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAS2R14 Q9NYV8 8/20 0.71
MEN1 O00255 2/20 0.71
KMT2A Q03164 2/20 0.71
CNR2 P34972 6/20 0.70
PTPN1 P18031 1/20 0.62
MAPT P10636 1/20 0.61
CA2 P00918 1/20 0.61
HSD11B1 P28845 1/20 0.61
ALDH1A1 P00352 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
CXCR3 P49682 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3837668 0.88 CNR2 (0.71) TAS2R14MEN1KMT2ACNR2ALDH1A1
SCHEMBL3483545 0.88 TAS2R14 (0.58) TAS2R14MEN1KMT2ACNR2PTPN1
SCHEMBL6121673 0.87 KMT2A (0.58) TAS2R14MEN1KMT2ACNR2PTPN1
SCHEMBL4413527 0.87 HTR2A (0.75) TAS2R14MEN1KMT2ACNR2MAPT
SCHEMBL3817627 0.87 TAS2R14 (0.61) TAS2R14MEN1KMT2ACNR2MAPT
SCHEMBL4243334 0.87 BACE1 (0.71) TAS2R14MEN1KMT2ACNR2MAPT
SCHEMBL8911635 0.87 TAS2R14 (0.78) TAS2R14MEN1KMT2ACNR2MAPT
SCHEMBL5295487 0.85 TAS2R14 (0.64) TAS2R14MEN1KMT2ACNR2MAPT
SCHEMBL4924397 0.85 TAS2R14 (0.64) TAS2R14MEN1KMT2ACNR2MAPT
SCHEMBL4917430 0.85 CNR2 (0.68) TAS2R14MEN1KMT2ACNR2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117832615-A Functional additive, electrolyte and lithium-sulfur battery 江西微电新能源有限公司 2024-04-05 CN claimed
EP-2640721-A2 AGONISTS THAT ENHANCE BINDING OF INTEGRIN-EXPRESSING CELLS TO INTEGRIN RECEPTORS Texas Heart Institute (US) 2013-09-25 EP claimed
US-20130236434-A1 AGONISTS THAT ENHANCE BINDING OF INTEGRIN-EXPRESSING CELLS TO INTEGRIN RECEPTORS TEXAS HEART INSTITUTE (US) 2013-09-12 US claimed
WO-2012068251-A2 AGONISTS THAT ENHANCE BINDING OF INTEGRIN-EXPRESSING CELLS TO INTEGRIN RECEPTORS TEXAS HEART INSTITUTE (US) 2012-05-24 WO claimed
US-6187083-B1 INK COMPOSITION COMPRISING SELECTED INK VEHICLE, AMIDE VISCOSITY MODIFIER, CONDUCTIVE SULFONATE SALT ALL HAVING MELTING POINTS WITHIN SPECIFIED RANGE, COLORANT, OPTIONAL ANTIOXIDANT AND ULTRAVIOLET ABSORBER XEROX CORPORATION 2001-02-13 US claimed
EP-0446982-B1 Low-temperature bleaching compositions UNILEVER NV (NL) 1994-10-26 EP claimed
EP-0446982-A2 Low-temperature bleaching compositions UNILEVER N.V. (NL) 1991-09-18 EP claimed
US-12636274-B2 Pharmaceutical compositions and methods for systemic treatment of solid tumors 7 HILLS PHARMA INC. (US) 2026-05-26 US disclosed
US-12201686-B2 Compositions including a therapeutic antibodies and/or a checkpoint inhibitor and an integrin activating compound 7 HILLS PHARMA INC. (US) 2025-01-21 US disclosed
US-20240189360-A1 COMPOSITIONS AND METHODS TO IMPROVE THE HOMING AND GRAFTING OF HEMATOPOETIC STEM CELLS 7 HILLS PHARMA INC. (US) 2024-06-13 US disclosed
CN-117832615-A Functional additive, electrolyte and lithium-sulfur battery 江西微电新能源有限公司 2024-04-05 CN disclosed
US-11484524-B2 Compositions and methods to improve adoptive cell therapies 7 Hills Pharma LLC (US) 2022-11-01 US disclosed
CN-107820429-B Novel compositions and methods for immunotherapy comprising small molecule integrin receptor-ligand agonist adjuvants 7山药物有限责任公司 2022-08-16 CN disclosed
US-7868194-B2 Process for the preparation of 21-hydroxy steroids with control of the epimeric distribution at the C-21 position INDUSTRIALE CHIMICA S.R.L. (IT) 2011-01-11 US disclosed
EP-1809649-B1 PROCESS FOR THE PREPARATION OF 21-HYDROXY STEROIDS WITH CONTROL OF THE EPIMERIC DISTRIBUTION AT THE C-21 POSITION IND CHIMICA SRL (IT) 2010-03-17 EP disclosed
US-20080114180-A1 Process for the Preparation of 21-Hydroxy Steroids with Control of the Epimeric Distribution at the C-21 Position INDUSTRIALE CHIMICA S.R.L. (IT) 2008-05-15 US disclosed
EP-1809649-A1 PROCESS FOR THE PREPARATION OF 21-HYDROXY STEROIDS WITH CONTROL OF THE EPIMERIC DISTRIBUTION AT THE C-21 POSITION INDUSTRIALE CHIMICA S.r.l. (IT) 2007-07-25 EP disclosed
WO-2006045745-A1 PROCESS FOR THE PREPARATION OF 21-HYDROXY STEROIDS WITH CONTROL OF THE EPIMERIC DISTRIBUTION AT THE C-21 POSITION INDUSTRIALE CHIMICA S.R.L. (IT) 2006-05-04 WO disclosed
US-6187083-B1 INK COMPOSITION COMPRISING SELECTED INK VEHICLE, AMIDE VISCOSITY MODIFIER, CONDUCTIVE SULFONATE SALT ALL HAVING MELTING POINTS WITHIN SPECIFIED RANGE, COLORANT, OPTIONAL ANTIOXIDANT AND ULTRAVIOLET ABSORBER XEROX CORPORATION 2001-02-13 US disclosed
CN-1117291-A 4-Hydroxy-pyran-2-one derivatives for the treatment of retroviral infections UPJOHN CO (US) 1996-02-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11484524-B2 Compositions and methods to improve adoptive cell therapies ITGB7, ITGB1, ITGA1 TAS2R14 3597/4885MEN1 2065/4885KMT2A 2131/4885
US-20080114180-A1 Process for the Preparation of 21-Hydroxy Steroids with Control of the Epimeric Distribution at the C-21 Position CYP17A1, CYP21A2, HSD17B7 TAS2R14 4575/4885MEN1 303/4885KMT2A 2463/4885
US-12636274-B2 Pharmaceutical compositions and methods for systemic treatment of solid tumors CD4, VCAM1, ITGA1 TAS2R14 1594/4885MEN1 1041/4885KMT2A 2861/4885
US-20130236434-A1 AGONISTS THAT ENHANCE BINDING OF INTEGRIN-EXPRESSING CELLS TO INTEGRIN RECEPTORS ITGB7, ITGAL, ITGB1 TAS2R14 1478/4885MEN1 3676/4885KMT2A 4144/4885
US-12201686-B2 Compositions including a therapeutic antibodies and/or a checkpoint inhibitor and an integrin activating compound CD47, CD274, ITGB1 TAS2R14 3225/4885MEN1 2026/4885KMT2A 1594/4885
US-20240189360-A1 COMPOSITIONS AND METHODS TO IMPROVE THE HOMING AND GRAFTING OF HEMATOPOETIC STEM CELLS CXCL12, ITGB3, ITGB7 TAS2R14 4287/4885MEN1 3184/4885KMT2A 2114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.