Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.70 |
| ▸ | HTR2C | P28335 | 1/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.70 |
| ▸ | TAS2R14 | Q9NYV8 | 12/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300788 | 0.89 | TAS2R14 (0.77) | TAS2R14MEN1KMT2AALDH1A1PKM | |
| SCHEMBL5010583 | 0.86 | HTR2A (0.81) | HTR2AHTR2CSLC6A4TAS2R14MEN1 | |
| SCHEMBL5011454 | 0.83 | HTR2A (0.77) | HTR2AHTR2CSLC6A4TAS2R14MEN1 | |
| SCHEMBL5011732 | 0.82 | HTR2A (1.00) | HTR2AHTR2CSLC6A4TAS2R14MEN1 | |
| SCHEMBL5010582 | 0.80 | CNR2 (0.71) | HTR2AHTR2CSLC6A4TAS2R14MEN1 | |
| SCHEMBL5011430 | 0.79 | HTR2A (0.70) | HTR2AHTR2CSLC6A4TAS2R14MEN1 | |
| SCHEMBL5009431 | 0.78 | CNR2 (0.73) | HTR2AHTR2CSLC6A4TAS2R14MEN1 | |
| SCHEMBL1278616 | 0.77 | TAS2R14 (1.00) | TAS2R14MEN1KMT2ACXCR3PTGES | |
| SCHEMBL5011405 | 0.77 | HTR2A (0.70) | HTR2AHTR2CSLC6A4TAS2R14MEN1 | |
| SCHEMBL1278788 | 0.76 | TAS2R14 (0.97) | TAS2R14MEN1KMT2ACXCR3PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093919-A1 | USE OF N-BENZYL-N-(2-DIMETHYLAMINO-ETHYL)BENZENESULFONAMIDE DERIVATIVES FOR TREATING CENTRAL NERVOUS SYSTEM DISORDERS | DONGBU HITEK CO., LTD. (KR) | 2008-08-07 | — | — | WO | claimed |
| WO-2008093919-A1 | USE OF N-BENZYL-N-(2-DIMETHYLAMINO-ETHYL)BENZENESULFONAMIDE DERIVATIVES FOR TREATING CENTRAL NERVOUS SYSTEM DISORDERS | DONGBU HITEK CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |