Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.61 |
| ▸ | HTR7 | P34969 | 5/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.60 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.60 |
| ▸ | HRH2 | P25021 | 2/20 | 0.60 |
| ▸ | HRH1 | P35367 | 2/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.57 |
| ▸ | HTR1B | P28222 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | HTR1E | P28566 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8160104 | 0.92 | HTR1A (0.58) | HTR1AHTR7SIGMAR1TMEM97SLC6A2 | |
| SCHEMBL11631677 | 0.87 | MAPT (0.63) | HTR1AHTR7SIGMAR1TMEM97SLC6A2 | |
| SCHEMBL11162215 | 0.87 | KCNH2 (0.60) | HTR1AHTR7SIGMAR1TMEM97SLC6A2 | |
| SCHEMBL6005398 | 0.86 | HTR1A (0.59) | HTR1ASIGMAR1TMEM97SLC6A2HRH2 | |
| SCHEMBL10763277 | 0.85 | HTR1A (0.65) | HTR1AHTR7MAPTHTR2AHTR2C | |
| SCHEMBL20562281 | 0.85 | HTR1A (0.64) | HTR1AHTR7SIGMAR1MAPTDRD2 | |
| SCHEMBL14860445 | 0.85 | ALDH1A1 (0.60) | SIGMAR1MAPTDRD2CHRNA7 | |
| SCHEMBL23086717 | 0.85 | ALDH1A1 (0.54) | HTR1ASIGMAR1TMEM97SLC6A2HRH2 | |
| SCHEMBL3157629 | 0.85 | KMT2A (0.68) | HTR1AMAPTDRD2DRD4HTR2A | |
| SCHEMBL6003242 | 0.85 | KMT2A (0.54) | HTR1ASIGMAR1TMEM97SLC6A2HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001549-A | IMAGING ELEMENT CONTAINING ANTISTATIC AGENT | EASTMAN KODAK COMPANY (US) | 1999-12-14 | — | — | US | claimed |
| US-5641967-A | INCREASED PHOTOSTIMULATED LUMINESCENCE | EASTMAN KODAK COMPANY (US) | 1997-06-24 | — | — | US | claimed |
| WO-2008093920-A2 | 1,2-DIHYDRO-1-OXOPHTHALAZINYL DERIVATIVES HAVING BIOLOGICAL ACTIVITY ON SEROTONIN RECEPTORS 5-HT2A AND 5-HT2C, AND PREPARATION THEREOF | DONGBU HITEK CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |
| EP-1383772-B1 | NITROGEN-BASED CAMPTOTHECIN DERIVATIVES | CALIFORNIA PACIFIC MED CENTER (US) | 2006-08-30 | — | — | EP | disclosed |
| CN-1246323-C | Nitrogen-based camptothecin derivatives | CALIFORNIA PACIFIC MED CENTER (US) | 2006-03-22 | — | — | CN | disclosed |
| US-6933302-B2 | Nitrogen-based homo-camptothecin derivatives | CALIFORNIA PACIFIC MEDICAL CENTER (US) | 2005-08-23 | — | — | US | disclosed |
| US-6855720-B2 | Nitrogen-based camptothecin derivatives | CALIFORNIA PACIFIC MEDICAL CENTER (US) | 2005-02-15 | — | — | US | disclosed |
| US-6825207-B2 | ANTICANCER AGENTS | CALIFORNIA PACIFIC MEDICAL CENTER | 2004-11-30 | — | — | US | disclosed |
| EP-1228124-B1 | ELECTRICALLY CONDUCTIVE MICROGEL AND METHOD FOR PREPARING THE SAME | Q SYS CO LTD (KR) | 2004-11-03 | — | — | EP | disclosed |
| CN-1511159-A | Nitrogen-based camptothecin derivatives | ����������̫ƽ��ҽѧ���� | 2004-07-07 | — | — | CN | disclosed |
| US-20040063740-A1 | For treatment of cancer | SUTTER WEST BAY HOSPITALS, DBA CALIFORNIA PACIFIC MEDICAL CENTER | 2004-04-01 | — | — | US | disclosed |
| US-4214047-A | Photographic elements having hydrophilic colloid layers containing hydrophobic addenda uniformly loaded in latex polymer particles | EASTMAN KODAK COMPANY (US) | 1980-07-22 | — | — | US | disclosed |
| US-4203716-A | Photographic elements having hydrophilic colloid layers containing hydrophobic addenda uniformly loaded in latex polymer particles | EASTMAN KODAK COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4199363-A | Processes for achieving uniform, efficient distribution of hydrophobic materials through hydrophilic colloid layers and loaded latex compositions | EASTMAN KODAK COMPANY (US) | 1980-04-22 | — | — | US | disclosed |
| US-4193800-A | COLOR DIFFUSION TRANSFER, POLYMER HAVING ACRYLOLAMINOPHENYL AMMONIUM UNITS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1980-03-18 | — | — | US | disclosed |
| US-4133687-A | Photographic elements having hydrophilic colloid layers containing compounds having activator precursors and hydrophobic developing agents uniformly loaded in latex polymer particles | EASTMAN KODAK COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4092416-A | Benzopyrone derivatives exhibiting anti-allergic activity | BOEHRINGER MANNHEIM GMBH (DT) | 1978-05-30 | — | — | US | disclosed |
| US-4070189-A | CATIONIC POLYBENZYLVINYL AMMONIUM OR PHOSPHONIUM SALT | EASTMAN KODAK COMPANY (US) | 1978-01-24 | — | — | US | disclosed |
| US-4055429-A | Inhibitor barrier layers for photographic materials | EASTMAN KODAK COMPANY (US) | 1977-10-25 | — | — | US | disclosed |
| US-3958995-A | Photographic elements containing cross-linked mordants and processes of preparing said elements | EASTMAN KODAK COMPANY (US) | 1976-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063740-A1 | For treatment of cancer | MGMT, PAICS, DCK | HTR1A 1728/4885HTR7 541/4885SIGMAR1 4740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.