Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CDC25B | P30305 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246864 | 0.88 | NR4A1 (0.52) | NR4A1NR4A2NR4A3MEN1KMT2A | |
| SCHEMBL10925556 | 0.87 | NR4A1 (0.48) | NR4A1NR4A2NR4A3MEN1KMT2A | |
| SCHEMBL5659885 | 0.83 | ALDH1A1 (0.45) | NR4A1NR4A2NR4A3MEN1KMT2A | |
| SCHEMBL27665302 | 0.81 | NR4A1 (0.50) | NR4A1NR4A2NR4A3MEN1KMT2A | |
| SCHEMBL5010784 | 0.79 | TDP1 (0.56) | NR4A1NR4A2NR4A3MEN1KMT2A | |
| SCHEMBL5011022 | 0.79 | MEN1 (0.50) | NR4A1NR4A2NR4A3MEN1KMT2A | |
| SCHEMBL4814494 | 0.76 | NR4A1 (0.52) | NR4A1NR4A2NR4A3MEN1KMT2A | |
| SCHEMBL219736 | 0.75 | ATM (0.54) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL4818412 | 0.75 | NR4A1 (0.50) | NR4A1NR4A2NR4A3MEN1KMT2A | |
| SCHEMBL5012402 | 0.75 | NR4A1 (0.55) | NR4A1NR4A2NR4A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508273-A | ARALKYLPHOSPHONATES FOR OSTEOPOROSIS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |
| EP-0061910-B1 | NOVEL SUBSTITUTED IMIDAZOLES AND TRIAZOLES, FUNGICIDAL COMPOSITIONS CONTAINING THEM, THE USE THEREOF FOR COMBATING FUNGI AND PROCESSES FOR THE PREPARATION OF INTERMEDIATES FOR MAKING THE IMIDAZOLES AND TRIAZOLES | ROHM AND HAAS COMPANY (US) | 1986-08-27 | — | — | EP | disclosed |
| EP-0061910-A2 | Novel substituted imidazoles and triazoles, fungicidal compositions containing them, the use thereof for combating fungi and processes for the preparation of intermediates for making the imidazoles and triazoles | ROHM AND HAAS COMPANY (US) | 1982-10-06 | — | — | EP | disclosed |