SCHEMBL5010820

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5013610	0.92	HTT (0.45)	HTTRECQLALDH1A1KMT2ATDP1
	SCHEMBL5012188	0.90	HTT (0.42)	HTTRECQLKMT2ANPC1RAB9A
	SCHEMBL5008214	0.90	HTT (0.41)	HTTRECQLALDH1A1KMT2ATDP1
	SCHEMBL14587761	0.90	HTT (0.39)	HTTRECQLALDH1A1KMT2ATDP1
	SCHEMBL5013398	0.89	HTT (0.44)	HTTRECQLALDH1A1KMT2ATDP1
	SCHEMBL5010563	0.86	HTT (0.41)	HTTRECQLALDH1A1KMT2ATDP1
	SCHEMBL5010664	0.85	HTT (0.41)	HTTRECQLALDH1A1KMT2ATDP1
	SCHEMBL14297710	0.84	CYP2C19 (0.41)	HTTRECQLALDH1A1KMT2ATDP1
	SCHEMBL14587757	0.84	ALDH1A1 (0.47)	HTTRECQLALDH1A1KMT2ATDP1
	SCHEMBL5010646	0.83	CYP2C19 (0.41)	HTTRECQLALDH1A1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.