SCHEMBL5010856

SCHEMBL5010856

Cc1ccc(-c2ccc(-c3ccc(C)cc3)n2-c2ccc(O)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.61
MEN1 O00255 4/20 0.61
KMT2A Q03164 4/20 0.61
KDM4E B2RXH2 3/20 0.61
ACHE P22303 1/20 0.52
PTGS2 P35354 1/20 0.50
ALDH1A1 P00352 6/20 0.48
HTT P42858 2/20 0.43
AR P10275 1/20 0.41
PKM P14618 1/20 0.40
MAPK1 P28482 1/20 0.40
GAA P10253 1/20 0.40
POLB P06746 1/20 0.40
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13231751 0.89 PTGS2 (0.58) MAPTMEN1KMT2AKDM4EPTGS2
SCHEMBL6283140 0.80 MAPT (0.49) MAPTMEN1KMT2AKDM4EPTGS2
SCHEMBL5012531 0.80 ALDH1A1 (0.52) MAPTMEN1KMT2AKDM4EPTGS2
SCHEMBL12103668 0.80 ALDH1A1 (0.52) MAPTMEN1KMT2AKDM4EPTGS2
SCHEMBL5134545 0.80 MEN1 (0.61) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL5010875 0.79 MAPK1 (0.59) MAPTMEN1KMT2AKDM4EPTGS2
SCHEMBL12103473 0.77 MAPK1 (0.53) MAPTMEN1KMT2AKDM4EPTGS2
SCHEMBL6287121 0.77 MEN1 (0.55) MAPTMEN1KMT2AKDM4EPTGS2
SCHEMBL5014194 0.76 PTGS2 (0.46) MAPTMEN1KMT2AKDM4EPTGS2
SCHEMBL6287200 0.75 MEN1 (0.53) MAPTMEN1KMT2AKDM4EPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1389626-B1 Aromatic copolymers of pyrroles and an electroluminescent element using the same KOREA INST SCI & TECH (KR) 2008-12-31 EP disclosed
US-6780950-B2 Pyrrole compounds, polymers thereof and EL element using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2004-08-24 US disclosed
US-20040034189-A1 Pyrrole compounds, polymers thereof and EL element using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 2004-02-19 US disclosed
EP-1389626-A1 Aromatic copolymers of pyrroles and an electroluminescent element using the same Korea Institute of Science and Technology (KR) 2004-02-18 EP disclosed