Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.32 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.32 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.32 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25926613 | 0.80 | KDM4E (0.42) | KDM4EHTTTSHRALDH1A1NPSR1 | |
| SCHEMBL3701211 | 0.78 | ALDH1A1 (0.37) | KDM4EHTTTSHRALDH1A1NPSR1 | |
| SCHEMBL4505828 | 0.75 | HTT (0.39) | KDM4EHTTTSHRALDH1A1GAA | |
| SCHEMBL2306361 | 0.74 | KDM4E (0.40) | KDM4EHTTTSHRALDH1A1NPSR1 | |
| SCHEMBL3751398 | 0.74 | KDM4E (0.40) | KDM4EHTTTSHRALDH1A1NPSR1 | |
| SCHEMBL2357083 | 0.74 | KDM4E (0.40) | KDM4EHTTTSHRALDH1A1NPSR1 | |
| SCHEMBL12703966 | 0.74 | KDM4E (0.38) | KDM4EHTTTSHRALDH1A1HSD17B10 | |
| SCHEMBL4506686 | 0.74 | KDM4E (0.38) | KDM4EHTTTSHRALDH1A1HSD17B10 | |
| SCHEMBL5054243 | 0.72 | ALDH1A1 (0.33) | KDM4EHTTTSHRALDH1A1NPSR1 | |
| SCHEMBL2310406 | 0.72 | KDM4E (0.42) | KDM4EHTTTSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888597-A2 | ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006120563-A2 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2006-11-16 | — | — | WO | disclosed |