Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436276 | 0.89 | ATM (0.56) | HPGDGAAALDH1A1KMT2AMAPT | |
| SCHEMBL2113444 | 0.87 | ALDH1A1 (0.64) | HPGDGAAALDH1A1KMT2AMAPT | |
| SCHEMBL8510525 | 0.87 | GAA (0.51) | HPGDGAAALDH1A1KMT2AMAPT | |
| SCHEMBL3849870 | 0.86 | LMNA (0.54) | HPGDGAAALDH1A1KMT2AMAPT | |
| SCHEMBL5009458 | 0.84 | ALDH1A1 (0.61) | HPGDGAAALDH1A1KMT2AMAPT | |
| SCHEMBL9052673 | 0.82 | GAA (0.60) | HPGDGAAALDH1A1KMT2AMAPT | |
| SCHEMBL11067105 | 0.81 | ADRB1 (0.74) | HPGDGAAALDH1A1KMT2AMAPT | |
| SCHEMBL8759118 | 0.81 | ALDH1A1 (0.77) | GAAALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL13087951 | 0.80 | GAA (0.65) | HPGDGAAALDH1A1KMT2AMAPT | |
| SCHEMBL11808012 | 0.79 | ALDH1A1 (0.67) | HPGDGAAALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022118966-A1 | AGENT FOR PROMOTING NUCLEIC ACID MOLECULE UPTAKE INTO CELLS, PHARMACEUTICAL COMPOSITION, AND NOVEL COMPOUND | 国立大学法人京都大学 | 2022-06-09 | — | — | WO | disclosed |
| WO-2008093920-A2 | 1,2-DIHYDRO-1-OXOPHTHALAZINYL DERIVATIVES HAVING BIOLOGICAL ACTIVITY ON SEROTONIN RECEPTORS 5-HT2A AND 5-HT2C, AND PREPARATION THEREOF | DONGBU HITEK CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |