Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.49 |
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27645138 | 0.84 | HTR1A (0.60) | SIGMAR1HTR1ADRD2HTR2ACCR3 | |
| SCHEMBL27666117 | 0.81 | HTR1A (0.58) | SIGMAR1HTR1ADRD2HTR2AMEN1 | |
| SCHEMBL5015053 | 0.79 | SIGMAR1 (0.49) | SIGMAR1HTR1ADRD2HTR2ACCR3 | |
| SCHEMBL27645231 | 0.78 | HTR1A (0.51) | SIGMAR1HTR1ADRD2HTR2ACCR3 | |
| SCHEMBL5537393 | 0.70 | SIGMAR1 (0.80) | SIGMAR1HTR1ADRD2HTR2ACCR3 | |
| SCHEMBL5544273 | 0.69 | SIGMAR1 (0.78) | SIGMAR1HTR1ADRD2HTR2ACCR3 | |
| SCHEMBL5535816 | 0.69 | SIGMAR1 (0.78) | SIGMAR1HTR1ADRD2HTR2ACCR3 | |
| SCHEMBL8092982 | 0.69 | SIGMAR1 (0.85) | SIGMAR1CCR3MEN1KMT2A | |
| SCHEMBL30671734 | 0.68 | SIGMAR1 (1.00) | SIGMAR1HTR1ADRD2HTR2ACCR3 | |
| SCHEMBL27666166 | 0.67 | HTR1A (0.43) | SIGMAR1HTR1ADRD2HTR2ACCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |