SCHEMBL5012065

SCHEMBL5012065

C=CCOC(CCO)OC(=O)C(=C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11555072 0.87 ALDH1A1 (0.35) TSHRALDH1A1TDP1
SCHEMBL10799542 0.86
SCHEMBL29776139 0.85 TDP1 (0.33) TSHRTDP1
SCHEMBL11555526 0.83 TSHR (0.35) TSHRALDH1A1
SCHEMBL8965806 0.82 TSHR (0.42) TSHRALDH1A1
SCHEMBL15901830 0.81 THRB (0.38) TSHRALDH1A1
SCHEMBL14695691 0.79 TSHR (0.34) TSHRALDH1A1
SCHEMBL16094200 0.78 TSHR (0.38) TSHRALDH1A1
SCHEMBL15901805 0.78 ALDH1A1 (0.41) TSHRALDH1A1
SCHEMBL9003015 0.76 TSHR (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1963402-A2 PROCESS FOR THE PRODUCTION OF MONODISPERSE AND NARROW DISPERSE MONOFUNCTIONAL SILICONES Johnson and Johnson Vision Care, Inc. (US) 2008-09-03 EP claimed
US-20060229423-A1 Process for the production of monodisperse and narrow disperse monofunctional silicones JOHNSON & JOHNSON VISION CARE, INC. 2006-10-12 US claimed
WO-2006102050-A2 PROCESS FOR THE PRODUCTION OF MONODISPERSE AND NARROW DISPERSE MONOFUNCTIONAL SILICONES JOHNSON & JOHNSON VISION CARE, INC. (US) 2006-09-28 WO claimed
US-12545803-B2 Coating agent, resin member, and production method therefor KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2026-02-10 US disclosed
US-20230407127-A1 COATING AGENT, RESIN MEMBER, AND PRODUCTION METHOD THEREFOR KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2023-12-21 US disclosed
EP-1963402-A2 PROCESS FOR THE PRODUCTION OF MONODISPERSE AND NARROW DISPERSE MONOFUNCTIONAL SILICONES Johnson and Johnson Vision Care, Inc. (US) 2008-09-03 EP disclosed
US-20060229423-A1 Process for the production of monodisperse and narrow disperse monofunctional silicones JOHNSON & JOHNSON VISION CARE, INC. 2006-10-12 US disclosed
WO-2006102050-A2 PROCESS FOR THE PRODUCTION OF MONODISPERSE AND NARROW DISPERSE MONOFUNCTIONAL SILICONES JOHNSON & JOHNSON VISION CARE, INC. (US) 2006-09-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545803-B2 Coating agent, resin member, and production method therefor SEM1, CDH1, NOTUM TSHR 4269/4885ALDH1A1 660/4885TDP1 4251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.