Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3812721 | 0.92 | KDM4E (0.44) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL3815329 | 0.90 | KDM4E (0.53) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL4965584 | 0.88 | KDM4E (0.45) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL13997408 | 0.88 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL5007881 | 0.88 | KDM4E (0.47) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL5010988 | 0.83 | KDM4E (0.36) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL4021949 | 0.82 | KDM4E (0.36) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL3819928 | 0.81 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL3810509 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL3820645 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1HPGDTSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312167-A1 | 4'' Amino Linked Macrolides Useful for the Treatment of Microbial Infections | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR (HR) | 2008-12-18 | — | — | US | disclosed |
| US-20080312167-A1 | 4'' Amino Linked Macrolides Useful for the Treatment of Microbial Infections | GLAXOSMITHKLINE ISTRAZIVACKI CENTAR (HR) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312167-A1 | 4'' Amino Linked Macrolides Useful for the Treatment of Microbial Infections | IL4I1, IL4, TLR5 | KDM4E 1535/4885ALDH1A1 2548/4885HPGD 2512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.