Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646390 | 0.70 | KMT2A (0.45) | MAPTALDH1A1GAANPSR1USP2 | |
| SCHEMBL5682210 | 0.67 | KCNA3 (0.49) | OPRM1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL11117905 | 0.65 | OPRM1 (0.58) | OPRM1SMN1; SMN2 | |
| SCHEMBL8561734 | 0.65 | OPRM1 (0.49) | OPRM1MAPTALDH1A1CYP1A2ALOX15 | |
| SCHEMBL5678119 | 0.65 | SMN1; SMN2 (0.50) | OPRM1ALDH1A1GAACYP2C9SMN1; SMN2 | |
| SCHEMBL20372758 | 0.64 | LMNA (0.47) | MAPTTP53ALDH1A1GAAMAPK1 | |
| SCHEMBL21867155 | 0.64 | OPRM1 (0.48) | OPRM1MAPTALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL11118382 | 0.63 | OPRM1 (0.55) | OPRM1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL20565645 | 0.63 | OPRM1 (0.47) | OPRM1MAPTALOX15POLB | |
| SCHEMBL5321983 | 0.62 | SMN1; SMN2 (0.51) | MAPTTP53ALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673083-A4 | N-SUBSTITUTED AZACYCLES | BAYER CROPSCIENCE AG (DE) | 2008-12-17 | — | — | EP | disclosed |
| EP-1673083-A2 | N-SUBSTITUTED AZACYCLES | FMC CORPORATION (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005036961-A2 | N-SUBSTITUTED AZACYCLES | FMC CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |