Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 8/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | MMP10 | P09238 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5012781 | 0.89 | PDE2A (0.38) | PDE2AMMP3MMP1MMP9MMP8 | |
| SCHEMBL645639 | 0.78 | SLC6A2 (0.40) | PDE2ASLC6A2SLC6A4 | |
| SCHEMBL646801 | 0.74 | SLC6A2 (0.43) | PDE2AMMP3MMP1MMP9MMP8 | |
| SCHEMBL646388 | 0.71 | KCNH2 (0.48) | MMP3MMP1MMP9MMP8MMP13 | |
| SCHEMBL648546 | 0.69 | RXRA (0.35) | PDE2AMMP3MMP1MMP9MMP8 | |
| SCHEMBL647940 | 0.65 | KCNH2 (0.48) | MMP3MMP1MMP9MMP8MMP13 | |
| SCHEMBL31469761 | 0.65 | SCN10A (0.37) | MMP3MMP1MMP9MMP8MMP13 | |
| SCHEMBL5237277 | 0.65 | DRD2 (0.54) | MMP3MMP1MMP9MMP8MMP13 | |
| SCHEMBL14893597 | 0.65 | NR1I2 (0.72) | PDE2AMMP3MMP1MMP9MMP8 | |
| SCHEMBL3543085 | 0.62 | EPHX1 (0.48) | PDE2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673083-A4 | N-SUBSTITUTED AZACYCLES | BAYER CROPSCIENCE AG (DE) | 2008-12-17 | — | — | EP | disclosed |
| EP-1673083-A2 | N-SUBSTITUTED AZACYCLES | FMC CORPORATION (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005036961-A2 | N-SUBSTITUTED AZACYCLES | FMC CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |