Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MMP10 | P09238 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5237277 | 0.76 | DRD2 (0.54) | SLC6A2SLC6A4MMP3MMP1MMP9 | |
| SCHEMBL5012790 | 0.76 | SLC6A2 (0.44) | SLC6A2SLC6A4MMP3MMP1MMP9 | |
| SCHEMBL645639 | 0.74 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3PDE2A | |
| SCHEMBL5012784 | 0.74 | PDE2A (0.39) | SLC6A2SLC6A4MMP3MMP1MMP9 | |
| SCHEMBL7289577 | 0.73 | MMP3 (0.45) | SLC6A2SLC6A4MMP3MMP1MMP9 | |
| SCHEMBL648828 | 0.72 | BCHE (0.51) | SLC6A2SLC6A4LIPEKCNH2ALDH1A1 | |
| SCHEMBL647493 | 0.72 | GPR119 (0.52) | SLC6A2SLC6A4LIPEKCNH2ALDH1A1 | |
| SCHEMBL4626514 | 0.72 | SLC6A2 (0.72) | SLC6A2SLC6A4 | |
| SCHEMBL31469761 | 0.72 | SCN10A (0.37) | SLC6A2SLC6A4MMP3MMP1MMP9 | |
| Hydrochloric Acid SCHEMBL3960882 | 0.71 | SLC6A2 (0.72) | SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119563-B2 | N-substituted azacycles | FMC CORPORATION (US) | 2012-02-21 | — | — | US | disclosed |
| US-8119563-B2 | N-substituted azacycles | FMC CORPORATION (US) | 2012-02-21 | — | — | US | disclosed |
| US-8119563-B2 | N-substituted azacycles | FMC CORPORATION (US) | 2012-02-21 | — | — | US | disclosed |
| US-20090215821-A1 | N-Substituted Azacycles | FMC CORPORATION | 2009-08-27 | — | — | US | disclosed |
| US-20090215821-A1 | N-Substituted Azacycles | FMC CORPORATION | 2009-08-27 | — | — | US | disclosed |
| US-20090215821-A1 | N-Substituted Azacycles | FMC CORPORATION | 2009-08-27 | — | — | US | disclosed |
| EP-1673083-A4 | N-SUBSTITUTED AZACYCLES | BAYER CROPSCIENCE AG (DE) | 2008-12-17 | — | — | EP | disclosed |
| US-20080039631-A1 | Process For Preparing N-(Substituted Arylmethyl) -4-Substituted-4-(Disubstituted Methyl) Piperidines And Intermediates | BAYER CROP SCIENCE AG (DE) | 2008-02-14 | — | — | US | disclosed |
| US-20080039631-A1 | Process For Preparing N-(Substituted Arylmethyl) -4-Substituted-4-(Disubstituted Methyl) Piperidines And Intermediates | BAYER CROP SCIENCE AG (DE) | 2008-02-14 | — | — | US | disclosed |
| US-20080039631-A1 | Process For Preparing N-(Substituted Arylmethyl) -4-Substituted-4-(Disubstituted Methyl) Piperidines And Intermediates | BAYER CROP SCIENCE AG (DE) | 2008-02-14 | — | — | US | disclosed |
| EP-1791828-A1 | PROCESS FOR PREPARING N-(SUBSTITUTED ARYLMETHYL)-4-SUBSTITUTED-4- (DISUBSTITUTED METHYL) PIPERIDINES AND INTERMEDIATES | Bayer CropScience AG (DE) | 2007-06-06 | — | — | EP | disclosed |
| EP-1673083-A2 | N-SUBSTITUTED AZACYCLES | FMC CORPORATION (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2006031674-A1 | PROCESS FOR PREPARING N-(SUBSTITUTED ARYLMETHYL)-4-SUBSTITUTED-4- (DISUBSTITUTED METHYL) PIPERIDINES AND INTERMEDIATES | BAYER CROPSCIENCE AG (DE) | 2006-03-23 | — | — | WO | disclosed |
| WO-2005036961-A2 | N-SUBSTITUTED AZACYCLES | FMC CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039631-A1 | Process For Preparing N-(Substituted Arylmethyl) -4-Substituted-4-(Disubstituted Methyl) Piperidines And Intermediates | POF1B, ZRANB2, POU5F1 | SLC6A2 4406/4885SLC6A4 3671/4885MMP3 4544/4885 |
| US-20090215821-A1 | N-Substituted Azacycles | DDT, UQCRB, DNMT1 | SLC6A2 1979/4885SLC6A4 3145/4885MMP3 4724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.