⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9406522 | 0.98 | SLC6A1 (0.41) | — | |
| SCHEMBL28348348 | 0.93 | SIGMAR1 (0.48) | — | |
| SCHEMBL4573782 | 0.87 | HRH3 (0.47) | — | |
| SCHEMBL4079555 | 0.86 | SIGMAR1 (0.48) | — | |
| SCHEMBL4725232 | 0.86 | — | — | |
| SCHEMBL7520554 | 0.86 | — | — | |
| SCHEMBL11799788 | 0.85 | SLC6A1 (0.48) | — | |
| SCHEMBL21184639 | 0.85 | SIGMAR1 (0.50) | — | |
| Hydrochloric Acid SCHEMBL3668452 | 0.84 | SIGMAR1 (0.46) | — | |
| SCHEMBL20854154 | 0.83 | SLC6A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118488982-A | Polyol catalyst for two-component polyurethane systems | 阿科玛法国公司 | 2024-08-13 | — | — | CN | claimed |
| US-6846827-B1 | Pyrimidine derivatives | ASTRAZENECA AB (SE) | 2005-01-25 | — | — | US | claimed |
| EP-1226126-B1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-01-05 | — | — | EP | claimed |
| EP-1226126-A1 | PYRIMIDINE DERIVATIVES | AstraZeneca AB (SE) | 2002-07-31 | — | — | EP | claimed |
| WO-2001027089-A1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-04-19 | — | — | WO | claimed |
| CN-118488982-A | Polyol catalyst for two-component polyurethane systems | 阿科玛法国公司 | 2024-08-13 | — | — | CN | disclosed |
| WO-2017120164-A1 | FUSED QUADRACYCLIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | Tabomedex Biosciences, LLC (US) | 2017-07-13 | — | — | WO | disclosed |
| EP-2963069-A1 | TERTIARY-NITROGEN-ATOM-CONTAINING LACTONE POLYMER HAVING POLYMERIZABLE GROUP, AND METHOD FOR PRODUCING SAME | Daicel Corporation (JP) | 2016-01-06 | — | — | EP | disclosed |
| US-20150376328-A1 | TERTIARY-NITROGEN-ATOM-CONTAINING LACTONE POLYMER HAVING POLYMERIZABLE GROUP, AND METHOD FOR PRODUCING SAME | DAICEL CORPORATION (JP) | 2015-12-31 | — | — | US | disclosed |
| WO-2008007835-A1 | 2,4-QUINAZOLINE DERIVATIVES HAVING ACTIVITY TO T-TYPE CALCIUM CHANNEL AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-01-17 | — | — | WO | disclosed |
| EP-1732896-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | Aventis Pharmaceuticals Inc. (US) | 2006-12-20 | — | — | EP | disclosed |
| EP-1201649-B1 | Glucocorticoid receptor modulators | PFIZER PROD INC (US) | 2006-05-31 | — | — | EP | disclosed |
| EP-1226126-B1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-01-05 | — | — | EP | disclosed |
| US-20020107235-A1 | Glucocorticoid receptor modulators | LIU KEVIN K (US) | 2002-08-08 | — | — | US | disclosed |
| EP-1226126-A1 | PYRIMIDINE DERIVATIVES | AstraZeneca AB (SE) | 2002-07-31 | — | — | EP | disclosed |
| EP-1201649-A1 | Glucocorticoid receptor modulators | Pfizer Products Inc. (US) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001027089-A1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-04-19 | — | — | WO | disclosed |
| US-4500452-A | NOT SUBJECT TO ENZYME DEACTIVATION | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1985-02-19 | — | — | US | disclosed |
| US-4472304-A | CARCINOSTATIC | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1984-09-18 | — | — | US | disclosed |
| US-3991076-A | Aminoalkylthiopyranopyrroles | AMERICAN HOECHST CORPORATION (US) | 1976-11-09 | — | — | US | disclosed |