Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2361637 | 0.79 | KDM4E (0.41) | HTTPDE10ATSHRKDM4EALDH1A1 | |
| SCHEMBL377269 | 0.78 | PDE10A (0.53) | HTTPDE10AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9348953 | 0.78 | TSPO (0.45) | PDE10AKDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL5183047 | 0.77 | POLB (0.55) | HTTPDE10ATSHRKDM4EALDH1A1 | |
| SCHEMBL377125 | 0.77 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| Water SCHEMBL8130350 | 0.75 | POLB (0.53) | HTTPDE10ATSHRKDM4EALDH1A1 | |
| SCHEMBL29113961 | 0.75 | HTT (0.50) | HTTPDE10ATSHRKDM4EALDH1A1 | |
| SCHEMBL18075813 | 0.75 | PDE10A (0.61) | PDE10ATSHRALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL4729382 | 0.74 | ERN1 (0.54) | HTTPDE10AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3234898 | 0.74 | GAA (0.56) | PDE10AKDM4EALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888817-A2 | METHOD FOR PRODUCING POROUS METAL-ORGANIC FRAMEWORK MATERIALS | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006125761-A2 | METHOD FOR PRODUCING POROUS METAL-ORGANIC FRAMEWORK MATERIALS | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-30 | — | — | WO | disclosed |