Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 4/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377125 | 0.84 | ALDH1A1 (0.52) | TSPOHSD17B10MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5013121 | 0.78 | HTT (0.45) | TSPOCYP1A2HSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL6036781 | 0.77 | ALDH1A1 (0.45) | TSPOHSD17B10MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5183047 | 0.76 | POLB (0.55) | HIF1AHSD17B10MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL18795122 | 0.76 | TDP1 (0.50) | TSPOHSD17B10MAPTSMN1; SMN2ALDH1A1 | |
| Water SCHEMBL8130350 | 0.74 | POLB (0.53) | HIF1AHSD17B10MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10970173 | 0.74 | MEN1 (0.50) | CYP2C19MAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8299332 | 0.74 | RAB9A (0.54) | CYP1A2CYP2C19MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7048658 | 0.74 | CYP1A2 (0.58) | GPR3CYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL6564086 | 0.73 | ALDH1A1 (0.49) | MAPTSMN1; SMN2ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273115-B1 | Chemiluminescent acridinium and phenanthridinium salts | ABBOTT LAB (US) | 1994-09-07 | — | — | EP | claimed |