Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.55 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29598743 | 0.98 | ALDH1A1 (0.61) | ALDH1A1RAB9ACHRM2CHRM4CHRM1 | |
| SCHEMBL2679227 | 0.89 | ALDH1A1 (0.52) | ALDH1A1RAB9ACHRM2CHRM4CHRM1 | |
| SCHEMBL6420791 | 0.84 | MAPT (0.56) | ALDH1A1RAB9AMAPTGAALMNA | |
| SCHEMBL6214071 | 0.83 | ALDH1A1 (0.51) | ALDH1A1RAB9ACHRM2CHRM4CHRM1 | |
| SCHEMBL10282674 | 0.83 | POLB (0.58) | ALDH1A1RAB9AMALT1HTTKDM4E | |
| SCHEMBL13779963 | 0.83 | KDM1A (0.57) | ALDH1A1RAB9APTGS2HTTKDM4E | |
| SCHEMBL5433861 | 0.83 | MALT1 (0.49) | ALDH1A1RAB9ACHRM2CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL27851912 | 0.82 | ALDH1A1 (0.50) | ALDH1A1RAB9AMALT1PTGS2HTT | |
| SCHEMBL28509553 | 0.81 | ALDH1A1 (0.67) | ALDH1A1RAB9ACHRM2CHRM4CHRM1 | |
| SCHEMBL30345222 | 0.81 | ALDH1A1 (0.74) | ALDH1A1RAB9ACHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884513-A1 | PYRAZOLE COMPOUND AND THERAPEUTIC AGENT FOR DIABETES COMPRISING THE SAME | Japan Tobacco, Inc. (JP) | 2008-02-06 | — | — | EP | claimed |
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | claimed |
| EP-4702000-A1 | ALKYLATION PROCESS | University of Liverpool (GB) | 2026-03-04 | — | — | EP | disclosed |
| WO-2024224034-A1 | ALKYLATION PROCESS | THE UNIVERSITY OF LIVERPOOL (GB) | 2024-10-31 | — | — | WO | disclosed |
| EP-1884513-A1 | PYRAZOLE COMPOUND AND THERAPEUTIC AGENT FOR DIABETES COMPRISING THE SAME | Japan Tobacco, Inc. (JP) | 2008-02-06 | — | — | EP | disclosed |
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | PYGL, GYS2, AGL | ALDH1A1 1278/4885RAB9A 2748/4885CHRM2 2132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.