SCHEMBL5013832

SCHEMBL5013832

CCC[CH]c1c(-c2ccccc2C)ccc2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.39
ALDH1A1 P00352 2/20 0.39
GAA P10253 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP1A2 P05177 5/20 0.37
TSHR P16473 2/20 0.37
HSD17B10 Q99714 2/20 0.36
HPGD P15428 1/20 0.36
ADORA2A P29274 1/20 0.35
GRIN2D O15399 1/20 0.35
GRIN3B O60391 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2A Q12879 1/20 0.35
GRIN2B Q13224 1/20 0.35
GRIN2C Q14957 1/20 0.35
GRIN3A Q8TCU5 1/20 0.35
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5010151 0.89 CYP2A6 (0.42) CYP2A6ALDH1A1GAATDP1L3MBTL1
SCHEMBL5010725 0.84 L3MBTL1 (0.37) ALDH1A1GAATDP1L3MBTL1TSHR
SCHEMBL5609949 0.82 TSHR (0.47) CYP2A6ALDH1A1GAATDP1L3MBTL1
SCHEMBL5012412 0.81 L3MBTL1 (0.39) CYP2A6ALDH1A1GAATDP1L3MBTL1
SCHEMBL1610694 0.73 NR1I2 (0.44) CYP2A6ALDH1A1GAATDP1L3MBTL1
SCHEMBL5008784 0.72 DNMT1 (0.38) CYP2A6ALDH1A1GAATDP1L3MBTL1
SCHEMBL5012483 0.72 TSHR (0.38) ALDH1A1GAACYP1A2TSHRHSD17B10
SCHEMBL16062615 0.71 TSHR (0.59) CYP2A6ALDH1A1TDP1L3MBTL1CYP1A2
SCHEMBL5008803 0.70 TSHR (0.36) ALDH1A1GAACYP1A2TSHRHSD17B10
SCHEMBL5609953 0.70 ALDH1A1 (0.41) ALDH1A1GAATDP1L3MBTL1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080207864-A1 Organosilanes, Process For Production of the Same, and Use Thereof SHARP KABUSHIKI KAISHA (JP) 2008-08-28 US disclosed