Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HEXA | P06865 | 1/20 | 0.33 |
| ▸ | HEXB | P07686 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5008803 | 0.98 | TSHR (0.36) | TSHRALDH1A1CYP1A2CYP2C19KDM4E | |
| SCHEMBL5008921 | 0.86 | TSHR (0.41) | TSHRALDH1A1CYP1A2CYP2C19KDM4E | |
| SCHEMBL5010170 | 0.84 | TSHR (0.40) | TSHRALDH1A1CYP1A2CYP2C19KDM4E | |
| SCHEMBL1610013 | 0.84 | TSHR (0.48) | TSHRALDH1A1CYP1A2CYP2C19KDM4E | |
| SCHEMBL5013849 | 0.79 | PTGS2 (0.35) | ALDH1A1TRPA1SMN1; SMN2DPP4HTR7 | |
| SCHEMBL4720996 | 0.78 | GRIN2D (0.40) | ALDH1A1TRPA1SMN1; SMN2DPP4HSD17B10 | |
| SCHEMBL6760277 | 0.77 | CNR1 (0.43) | ALDH1A1KDM4ESMN1; SMN2HTR7TLR8 | |
| SCHEMBL1611497 | 0.76 | TRPA1 (0.37) | TSHRALDH1A1CYP1A2TRPA1SMN1; SMN2 | |
| SCHEMBL1611320 | 0.72 | TSHR (0.45) | TSHRALDH1A1CYP1A2CYP2C19KDM4E | |
| SCHEMBL5013832 | 0.72 | CYP2A6 (0.39) | TSHRALDH1A1CYP1A2CYP2C19BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |