Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3138274 | 0.95 | EPHX1 (0.38) | EPHX1POLBALDH1A1CYP2C19CYP2C9 | |
| SCHEMBL1093413 | 0.92 | L3MBTL1 (0.42) | EPHX1POLBALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL5015462 | 0.84 | TSHR (0.36) | POLBALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL3128717 | 0.83 | TSHR (0.35) | TSHR | |
| SCHEMBL671675 | 0.78 | TSHR (0.45) | ALDH1A1TSHR | |
| SCHEMBL1695697 | 0.77 | TSHR (0.44) | ALDH1A1TSHR | |
| SCHEMBL10427162 | 0.75 | TSHR (0.42) | EPHX1ALDH1A1TSHR | |
| SCHEMBL10427135 | 0.75 | TSHR (0.42) | EPHX1ALDH1A1TSHR | |
| SCHEMBL673042 | 0.74 | TSHR (0.41) | ALDH1A1TSHR | |
| SCHEMBL8733208 | 0.74 | TSHR (0.41) | CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200582-A1 | High refractive index monomers, compositions and uses thereof | CIBA CORP. | 2008-08-21 | — | — | US | disclosed |
| EP-0940694-B1 | Photochromic curable composition | TOKUYAMA CORP (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-6194511-B1 | COMPRISING POLYMERIZABLE MONOMER CONTAINING SULFUR-CONTAINING (METH)ACRYLATE POLYMERIZABLE MONOMER AND PHOTOCHROMIC COMPOUND | TOKUYAMA CORPORATION (JP) | 2001-02-27 | — | — | US | disclosed |
| EP-0940694-A1 | Photochromic curable composition | TOKUYAMA CORPORATION (JP) | 1999-09-08 | — | — | EP | disclosed |