Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1093413 | 0.86 | L3MBTL1 (0.42) | TSHRELANESMN1; SMN2LMNAATM | |
| SCHEMBL5014108 | 0.84 | EPHX1 (0.41) | TSHRSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL3138274 | 0.80 | EPHX1 (0.38) | TSHRSMN1; SMN2NPSR1ALDH1A1POLB | |
| SCHEMBL3128717 | 0.80 | TSHR (0.35) | TSHR | |
| SCHEMBL671675 | 0.76 | TSHR (0.45) | TSHRALDH1A1 | |
| SCHEMBL1695697 | 0.74 | TSHR (0.44) | TSHRALDH1A1 | |
| SCHEMBL2392777 | 0.74 | ELANE (0.41) | ELANESMN1; SMN2MAPTLMNAXBP1 | |
| SCHEMBL10427162 | 0.73 | TSHR (0.42) | TSHRALDH1A1 | |
| SCHEMBL10427135 | 0.73 | TSHR (0.42) | TSHRALDH1A1 | |
| SCHEMBL673042 | 0.71 | TSHR (0.41) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200582-A1 | High refractive index monomers, compositions and uses thereof | CIBA CORP. | 2008-08-21 | — | — | US | disclosed |