Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | ACACA | Q13085 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014108 | 0.95 | EPHX1 (0.41) | EPHX1CYP2C19POLBALDH1A1CYP2C9 | |
| SCHEMBL1093413 | 0.88 | L3MBTL1 (0.42) | EPHX1POLBALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL5015462 | 0.80 | TSHR (0.36) | POLBALDH1A1SMN1; SMN2TSHRNPSR1 | |
| SCHEMBL3128717 | 0.79 | TSHR (0.35) | TSHR | |
| SCHEMBL671675 | 0.75 | TSHR (0.45) | ALDH1A1TSHR | |
| SCHEMBL1695697 | 0.73 | TSHR (0.44) | ALDH1A1TSHR | |
| SCHEMBL10427135 | 0.72 | TSHR (0.42) | EPHX1ALDH1A1TSHR | |
| SCHEMBL10427162 | 0.72 | TSHR (0.42) | EPHX1ALDH1A1TSHR | |
| SCHEMBL3138262 | 0.71 | ACACB (0.36) | ALDH1A1TSHRACACBACACA | |
| SCHEMBL673042 | 0.70 | TSHR (0.41) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139878-A2 | HIGH REFRACTIVE INDEX MONOMERS, COMPOSITIONS AND USES THEREOF | BASF SE (DE) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008101806-A2 | HIGH REFRACTIVE INDEX MONOMERS, COMPOSITIONS AND USES THEREOF | BASF SE (CH) | 2008-08-28 | — | — | WO | disclosed |
| US-20080200582-A1 | High refractive index monomers, compositions and uses thereof | CIBA CORP. | 2008-08-21 | — | — | US | disclosed |