Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447217 | 0.86 | MEN1 (0.40) | GHSRKMT2AMEN1NPY5RMMP13 | |
| SCHEMBL3245632 | 0.83 | MEN1 (0.42) | POLBKMT2AMEN1MMP13ALDH1A1 | |
| SCHEMBL4453688 | 0.83 | CETP (0.36) | GHSRKMT2ANPY5RMMP13ALDH1A1 | |
| SCHEMBL27782513 | 0.81 | SIRT5 (0.42) | GHSRSIRT5MMP13ALDH1A1HTT | |
| SCHEMBL6543839 | 0.81 | MAPT (0.40) | GHSRCYP2C19NPY5RMMP13ALDH1A1 | |
| SCHEMBL6544430 | 0.81 | MMP13 (0.42) | CYP2C19NPY5RMMP13ALDH1A1 | |
| SCHEMBL3487106 | 0.80 | HSD17B1 (0.44) | KMT2AMEN1ALDH1A1HTTMAPT | |
| SCHEMBL3487759 | 0.80 | MAPT (0.42) | GHSRPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL3488461 | 0.80 | DHODH (0.38) | KMT2AMEN1HTTMAPT | |
| SCHEMBL6543697 | 0.79 | MAPT (0.38) | MMP13ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1982718-A1 | ANTI-CANCER PHARMACEUTICAL COMPOSITION | Daiichi Sankyo Company, Limited (JP) | 2008-10-22 | — | — | EP | disclosed |