SCHEMBL5014199

SCHEMBL5014199

C#Cc1cccc2cc3ccccc3c([Si](C)(C)C)c12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.39
ERBB2 P04626 1/20 0.39
FYN P06241 1/20 0.39
MAOA P21397 1/20 0.39
ACHE P22303 1/20 0.39
AHR P35869 1/20 0.39
CYP1A1 P04798 1/20 0.36
CYP1B1 Q16678 1/20 0.36
CES1 P23141 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP1 P29466 1/20 0.32
HIF1A Q16665 1/20 0.32
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29407832 0.80 CA1 (0.30) CA1CA2
SCHEMBL28414168 0.80 CA1 (0.30) CA1CA2
SCHEMBL3689065 0.76 ELANE (0.31) CYP1A2CYP1A1CYP1B1ALDH1A1HPGD
SCHEMBL12627478 0.75 ALDH1A1 (0.44) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL5012544 0.75 CYP2A6 (0.39) CYP1A2CYP1A1CYP1B1ALDH1A1HPGD
SCHEMBL9899758 0.72 HSD17B10 (0.36) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL20508231 0.71 CYP1B1 (0.46) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL3465692 0.70 NQO1 (0.33) ALDH1A1HPGDCA1CA2
SCHEMBL30918302 0.70 ALDH1A1 (0.41) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL937286 0.70 ALDH1A1 (0.41) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111040204-B Force-induced response dynamic polymer and application thereof 厦门天策材料科技有限公司 2023-01-24 CN disclosed
CN-111040110-B Force-induced response dynamic polymer and application thereof 厦门天策材料科技有限公司 2022-03-11 CN disclosed
CN-111378169-A Force-induced response hybrid crosslinked dynamic polymer 翁秋梅 2020-07-07 CN disclosed
CN-111378137-A Force-induced responsive polymer with multi-network structure 翁秋梅 2020-07-07 CN disclosed
CN-111171364-A Force-responsive polymer foam particle and preparation method thereof 翁秋梅 2020-05-19 CN disclosed
CN-111171365-A Force-responsive polymer foam composite material 翁秋梅 2020-05-19 CN disclosed
CN-111040204-A Force-induced response dynamic polymer and application thereof 翁秋梅 2020-04-21 CN disclosed
CN-111040110-A Force-induced response dynamic polymer and application thereof 翁秋梅 2020-04-21 CN disclosed
EP-1389626-B1 Aromatic copolymers of pyrroles and an electroluminescent element using the same KOREA INST SCI & TECH (KR) 2008-12-31 EP disclosed
US-6780950-B2 Pyrrole compounds, polymers thereof and EL element using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2004-08-24 US disclosed
US-20040034189-A1 Pyrrole compounds, polymers thereof and EL element using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 2004-02-19 US disclosed
EP-1389626-A1 Aromatic copolymers of pyrroles and an electroluminescent element using the same Korea Institute of Science and Technology (KR) 2004-02-18 EP disclosed