SCHEMBL5014204

SCHEMBL5014204

C#Cc1cc([Si](C)(C)C)ccc1C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.31
ILK Q13418 1/20 0.31
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9538187 0.83 ACHE (0.32) ACHE
SCHEMBL8018559 0.78 EGFR (0.35) EGFRACHE
SCHEMBL28362746 0.78 ACHE (0.33) ACHE
SCHEMBL28439449 0.73
SCHEMBL4124729 0.73 ABL1 (0.30) ACHE
SCHEMBL3220960 0.73 TDP1 (0.42) ACHE
SCHEMBL3313456 0.72 ALDH1A1 (0.42) ACHE
SCHEMBL11663960 0.71 HDAC8 (0.34) EGFRILK
SCHEMBL3824007 0.70 ALDH1A1 (0.40) ACHE
SCHEMBL27594266 0.70 APP (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1389626-B1 Aromatic copolymers of pyrroles and an electroluminescent element using the same KOREA INST SCI & TECH (KR) 2008-12-31 EP disclosed
US-6780950-B2 Pyrrole compounds, polymers thereof and EL element using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2004-08-24 US disclosed
US-20040034189-A1 Pyrrole compounds, polymers thereof and EL element using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 2004-02-19 US disclosed
EP-1389626-A1 Aromatic copolymers of pyrroles and an electroluminescent element using the same Korea Institute of Science and Technology (KR) 2004-02-18 EP disclosed