Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2113444 | 0.84 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AHTR7TSHR | |
| SCHEMBL2114057 | 0.83 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AHTR7HTR1A | |
| SCHEMBL7416929 | 0.77 | ALDH1A1 (0.53) | ALDH1A1SLC6A4SLC6A2MEN1KMT2A | |
| SCHEMBL2114983 | 0.77 | HTR1A (0.73) | ALDH1A1HTR7L3MBTL1HTR1AHTR2A | |
| SCHEMBL5228101 | 0.76 | MEN1 (0.55) | ALDH1A1SLC6A4SLC6A2MEN1KMT2A | |
| SCHEMBL5010657 | 0.76 | MAPT (0.61) | MEN1KMT2AHTR7HTR1A | |
| SCHEMBL5010586 | 0.76 | GAA (0.51) | SLC6A4HTR7HTR1AHTR2AHTR2C | |
| SCHEMBL5009458 | 0.76 | ALDH1A1 (0.61) | ALDH1A1SLC6A4MEN1KMT2AHTR7 | |
| Hydrochloric Acid SCHEMBL9811592 | 0.76 | HTR1A (0.71) | ALDH1A1HTR7L3MBTL1HTR1AHTR2A | |
| SCHEMBL3436612 | 0.75 | MEN1 (0.48) | ALDH1A1MEN1KMT2AL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093920-A2 | 1,2-DIHYDRO-1-OXOPHTHALAZINYL DERIVATIVES HAVING BIOLOGICAL ACTIVITY ON SEROTONIN RECEPTORS 5-HT2A AND 5-HT2C, AND PREPARATION THEREOF | DONGBU HITEK CO., LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |