Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL5013320 | 0.86 | CA1 (0.39) | BBOX1TSHRMAPK1GMNNALDH1A1 | |
| SCHEMBL778055 | 0.86 | CA1 (0.46) | TSHRMAPK1ALDH1A1LMNACA1 | |
| SCHEMBL29104747 | 0.81 | CA2 (0.46) | TSHRALDH1A1LMNACA1CA2 | |
| SCHEMBL16038351 | 0.79 | CA2 (0.43) | TSHRMAPK1CA1CA2RECQL | |
| SCHEMBL2382465 | 0.77 | CA1 (0.42) | TSHRMAPK1ALDH1A1LMNATP53 | |
| SCHEMBL16045492 | 0.76 | APP (0.41) | LMNACA1CA2EPHX2BLM | |
| SCHEMBL778781 | 0.75 | CA1 (0.50) | TSHRALDH1A1LMNACA1CA2 | |
| Eprodisate SCHEMBL4422542 | 0.75 | ALDH1A1 (0.58) | BBOX1TSHRMAPK1GMNNALDH1A1 | |
| SCHEMBL8817616 | 0.75 | FAAH (0.46) | TSHRMAPK1CA1CA2RECQL | |
| SCHEMBL19092526 | 0.75 | CA2 (0.40) | TSHRMAPK1ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9118062-B2 | Anode and method of manufacturing the same, and battery and method of manufacturing the same | SONY CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20080311472-A1 | ANODE AND METHOD OF MANUFACTURING THE SAME, AND BATTERY AND METHOD OF MANUFACTURING THE SAME | SONY CORPORATION (JP) | 2008-12-18 | — | — | US | disclosed |