SCHEMBL5014432

SCHEMBL5014432

CO[Si](CCc1ccc(S(N)(=O)=O)cc1)(OC)OC

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 17/20 0.58
CA1 P00915 10/20 0.58
CA9 Q16790 9/20 0.58
CA12 O43570 7/20 0.58
CA4 P22748 4/20 0.58
CA6 P23280 2/20 0.58
CA5A P35218 2/20 0.58
CA7 P43166 2/20 0.58
CA14 Q9ULX7 2/20 0.58
CA5B Q9Y2D0 2/20 0.58
SMN1; SMN2 Q16637 1/20 0.54
ALDH1A1 P00352 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL332136 0.84 ALDH1A1 (0.41) CA2CA1CA9CA12CA4
SCHEMBL5848176 0.83 CA2 (0.41) CA2CA1CA9CA12CA4
Hydrochloric Acid SCHEMBL28172394 0.81 CA2 (0.40) CA2CA1CA9CA12CA4
SCHEMBL139733 0.81 TAAR1 (0.43) SMN1; SMN2
SCHEMBL4291669 0.79 TAAR1 (0.41) CA2SMN1; SMN2
SCHEMBL1162632 0.79 ALDH1A1 (0.38) CA2CA1CA9CA12CA4
SCHEMBL15806002 0.77 RCE1 (0.38) CA2CA1CA9CA12CA5A
SCHEMBL14959419 0.77 CA2 (0.63) CA2CA1CA9CA12CA4
SCHEMBL15806142 0.76 ALDH1A1 (0.49) CA2CA1CA9CA12CA4
SCHEMBL9660429 0.76 TAAR1 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470761-B2 Proton-conductive membranes and layers and methods for their production FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2008-12-30 US disclosed
EP-1323767-B1 Proton conducting membranes or layers and process for their fabrication FRAUNHOFER GES FORSCHUNG (DE) 2008-03-12 EP disclosed
US-20060058485-A1 Proton-conductive membranes and layers and methods for their production FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. 2006-03-16 US disclosed
US-6949616-B2 Proton-conductive membranes and layers and methods for their production FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2005-09-27 US disclosed
US-20030144450-A1 Proton-conductive membranes and layers and methods for their production FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. 2003-07-31 US disclosed
EP-1323767-A2 Proton conducting membranes or layers and process for their fabrication Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2003-07-02 EP disclosed