Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.44 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13026783 | 0.85 | HCAR3 (0.47) | HCAR3KEAP1SLC9A1HPGDKDM4E | |
| SCHEMBL904701 | 0.81 | HCAR3 (0.50) | HCAR3KEAP1SLC9A1HPGDKDM4E | |
| SCHEMBL14074965 | 0.80 | HCAR3 (0.43) | HCAR3KEAP1SLC9A1HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL27205663 | 0.80 | HCAR3 (0.49) | HCAR3KEAP1SLC9A1HPGDKDM4E | |
| SCHEMBL10287998 | 0.80 | HCAR3 (0.51) | HCAR3KEAP1SLC9A1HPGDKDM4E | |
| SCHEMBL8238198 | 0.79 | HCAR3 (0.46) | HCAR3KEAP1SLC9A1HPGDKDM4E | |
| SCHEMBL478164 | 0.78 | HCAR3 (0.50) | HCAR3KEAP1SLC9A1HPGDKDM4E | |
| SCHEMBL1939333 | 0.78 | HCAR3 (0.54) | HCAR3KEAP1SLC9A1HPGDKDM4E | |
| SCHEMBL3330921 | 0.78 | HCAR3 (0.50) | HCAR3KEAP1SLC9A1HPGDKDM4E | |
| SCHEMBL16406898 | 0.77 | CTNNB1 (0.43) | HCAR3KEAP1SLC9A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7419962-B2 | 3,6-bicyclolides | ENANTA PHARMACEUTICALS, INC. (US) | 2008-09-02 | — | — | US | disclosed |
| US-20060142214-A1 | 3,6-bicyclolides | ENANTA PHARMACEUTICALS, INC. | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142214-A1 | 3,6-bicyclolides | ABCB11, CYP2B6, CYP3A7 | HCAR3 318/4885KEAP1 1869/4885SLC9A1 2920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.