⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL242516 | 0.81 | EIF4A3 (0.39) | — | |
| Hydrochloric Acid SCHEMBL3932764 | 0.80 | ADRB2 (0.34) | — | |
| SCHEMBL19523306 | 0.78 | — | — | |
| SCHEMBL11659128 | 0.78 | — | — | |
| SCHEMBL21104304 | 0.78 | — | — | |
| SCHEMBL30462995 | 0.78 | KIF11 (0.37) | — | |
| SCHEMBL4636201 | 0.75 | SCN10A (0.42) | — | |
| SCHEMBL23680086 | 0.74 | — | — | |
| SCHEMBL24171458 | 0.73 | SCN10A (0.32) | — | |
| SCHEMBL269133 | 0.72 | PRKD3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7419962-B2 | 3,6-bicyclolides | ENANTA PHARMACEUTICALS, INC. (US) | 2008-09-02 | — | — | US | disclosed |
| EP-1830858-A2 | 3, 6-BICYCLOLIDES | Enanta Pharmaceuticals, Inc. (US) | 2007-09-12 | — | — | EP | disclosed |
| US-20060142214-A1 | 3,6-bicyclolides | ENANTA PHARMACEUTICALS, INC. | 2006-06-29 | — | — | US | disclosed |
| WO-2006063039-A2 | 3, 6-BICYCLOLIDES | ENANTA PHARMACEUTICALS, INC. (US) | 2006-06-15 | — | — | WO | disclosed |