Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.36 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13995079 | 0.90 | IDO1 (0.34) | IDO1 | |
| SCHEMBL5135430 | 0.90 | IDO1 (0.34) | IDO1 | |
| SCHEMBL13995069 | 0.88 | IDO1 (0.33) | IDO1 | |
| SCHEMBL14999151 | 0.88 | CYP1A2 (0.62) | CYP1A2CYP2A6MAPTTDP1KDM4E | |
| SCHEMBL29416731 | 0.84 | CYP1A2 (0.68) | CYP1A2CYP2A6MAPTTDP1HIF1A | |
| SCHEMBL2380918 | 0.84 | CYP1A2 (0.68) | CYP1A2CYP2A6MAPTTDP1HIF1A | |
| SCHEMBL260441 | 0.84 | CYP1A2 (0.68) | CYP1A2CYP2A6MAPTTDP1HIF1A | |
| SCHEMBL13995084 | 0.83 | ACHE (0.33) | CYP1A2MAPTTDP1KDM4EHPGD | |
| SCHEMBL24648194 | 0.80 | GPR84 (0.36) | MAPTTDP1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL13995059 | 0.80 | DHFR (0.45) | MAPTTDP1KDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957604-B1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-1957604-B1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-09-23 | — | — | EP | disclosed |
| US-8795847-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-08-05 | — | — | US | disclosed |
| US-8795847-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-08-05 | — | — | US | disclosed |
| US-8795847-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-08-05 | — | — | US | disclosed |
| US-20080303003-A1 | Novel Materials for Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
| US-20080303003-A1 | Novel Materials for Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080303003-A1 | Novel Materials for Organic Electroluminescent Devices | ANXA2, ANXA3, ANXA1 | CYP1A2 2362/4885CYP2A6 4103/4885MAPT 1988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.