SCHEMBL5014814

SCHEMBL5014814

C=CC(=O)OC(O)C[SiH2]O[SiH3]

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.33
ALDH1A1 P00352 3/20 0.31
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
CYP3A4 P08684 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5014835 0.82 TSHR (0.32) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8965849 0.73 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL5024466 0.73 TSHR (0.36) TSHRALDH1A1
SCHEMBL2137705 0.71
SCHEMBL4197867 0.71
SCHEMBL549537 0.71
SCHEMBL9546119 0.70 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL11193107 0.70
SCHEMBL27995286 0.70
SCHEMBL11233280 0.70 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7393911-B2 Organosilicon fine particles and method of producing same TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 2008-07-01 US disclosed
US-20060089478-A1 antireflection and antiblocking characteristics to synthetic polymer films and sheets when applied to their surface or caused to be contained, respectively, and adherence and slip characteristics to a skin care cosmetic material when caused to be contained TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 2006-04-27 US disclosed