Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 4/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10054032 | 0.78 | USP2 (0.37) | GAAALDH1A1KMT2ACYP3A4USP2 | |
| SCHEMBL2268647 | 0.77 | CHRNB4 (0.41) | CHRNB4CHRNA3CHRNB2CHRNA4MAPT | |
| SCHEMBL6782580 | 0.76 | AHR (0.45) | MAPTALDH1A1MAPK1TDP1MEN1 | |
| SCHEMBL13862088 | 0.76 | CA2 (0.39) | CHRNB4CHRNA3CHRNB2CHRNA4MAPT | |
| Hydrochloric Acid SCHEMBL20502990 | 0.75 | MAPT (0.42) | CHRNB4CHRNA3CHRNB2CHRNA4MAPT | |
| SCHEMBL6619829 | 0.73 | CA2 (0.36) | MAPTALDH1A1NR3C1NPC1 | |
| SCHEMBL7709944 | 0.73 | CYP3A4 (0.33) | KDM4EALDH1A1CYP3A4 | |
| SCHEMBL1168265 | 0.73 | GAA (0.40) | CHRNB4CHRNA3CHRNB2CHRNA4MAPT | |
| SCHEMBL5285093 | 0.72 | MAPT (0.39) | CHRNB4CHRNA3CHRNB2CHRNA4MAPT | |
| SCHEMBL27682747 | 0.72 | MAPT (0.39) | CHRNB4CHRNA3CHRNB2CHRNA4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329287-B2 | Oxidation dye composition for keratin fibers, comprising at least one oxidation dye, at least one associative polymer, at least one nonionic cellulose-based compound not comprising a C8-C30 fatty chain, and at least one cationic polymer with a charge density of greater than 1 meq/g and not comprising a C8-C30 fatty chain | L'OREAL S.A. (FR) | 2008-02-12 | — | — | US | disclosed |
| US-20040163186-A1 | Oxidation dye composition for keratin fibers, comprising at least one oxidation dye, at least one associative polymer, at least one nonionic cellulose-based compound not comprising a C8-C30 fatty chain, and at least one cationic polymer with a charge density of greater than 1 meq/g and not comprising a C8-C30 fatty chain | L'OREAL S.A. (FR) | 2004-08-26 | — | — | US | disclosed |
| US-6599328-B1 | Ready-to-use composition for oxidation dyeing of keratin fibers comprising oxidation dye, 2-electron or 4-electron oxidoreductase enzyme, and chitosan chosen from salified or chemically modified chitosan | L'OREAL S.A. (FR) | 2003-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040163186-A1 | Oxidation dye composition for keratin fibers, comprising at least one oxidation dye, at least one associative polymer, at least one nonionic cellulose-based compound not comprising a C8-C30 fatty chain, and at least one cationic polymer with a charge density of greater than 1 meq/g and not comprising a C8-C30 fatty chain | KRT18, ACAD10, SLC25A20 | CHRNB4 1503/4885CHRNA3 2040/4885CHRNB2 2469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.