ACAD10

Acyl-CoA dehydrogenase family member 10 · Q6JQN1 · ACAD10 on Sugi Atlas →

1,261 patent compounds predicted against ACAD10, 1,045 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Hydroxyfasudil (SCHEMBL123699)	1.00	1/20
Alisertib (SCHEMBL855823)	1.00	1/20
Mk-5108 (SCHEMBL1501371)	1.00	1/20
Mk-5108 (SCHEMBL1501374)	1.00	1/20
Gsk-1070916 (SCHEMBL4305006)	1.00	1/20
Alisertib (SCHEMBL854553)	0.98	1/20
Mk-5108 (SCHEMBL1501406)	0.98	1/20
Mk-5108 (SCHEMBL1501407)	0.98	1/20
Alisertib (SCHEMBL14125416)	0.97	1/20
SCHEMBL2389378	0.94	1/20
SCHEMBL2389355	0.89	1/20
SCHEMBL2392579	0.89	1/20
SCHEMBL12454978	0.89	1/20
SCHEMBL4316846	0.87	1/20
SCHEMBL1501124	0.87	1/20
SCHEMBL1501126	0.87	1/20
SCHEMBL2386771	0.87	1/20
SCHEMBL1501147	0.86	1/20
SCHEMBL1501150	0.86	1/20
Alisertib (SCHEMBL854552)	0.86	1/20

Clinical trials — most relevant to ACAD10 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease	PHASE3	COMPLETED
Effect of Montelukast Versus Co Enzyme in Sepsis	PHASE2/PHASE3	COMPLETED
CoQ10 and Exercise for Mitochondrial Dysfunction in Advance Kidney Disease	PHASE3	RECRUITING
Acetylcarnitine and Insulin Sensitivity	PHASE2	COMPLETED
Effect of Bezafibrate on Muscle Metabolism in Patients With Fatty Acid Oxidation Defects	PHASE2	COMPLETED
The Effects of Coenzyme A Combined With Abiraterone on Patients With CRPC	PHASE1/PHASE2	UNKNOWN
Autologous Hematopoietic Stem Cell Gene Therapy for Metachromatic Leukodystrophy and Adrenoleukodystrophy	PHASE1/PHASE2	UNKNOWN
Atorvastatin, L-Carnitine and Non-Alcoholic Steatohepatitis	PHASE2	UNKNOWN
Carnitine Consumption and Augmentation in Pulmonary Arterial Hypertension	PHASE1	COMPLETED
A Phase 1b Study of the Safety of REN001 in Patients With Fatty Acid Oxidation Disorders	PHASE1	COMPLETED
Fasting Tolerance in MCADD-infants	nan	UNKNOWN
Fatty Acid Oxidation Defects and Insulin Sensitivity	nan	COMPLETED
A Prospective Study of the Disease Characteristics of Adult Patients With Long Chain Fatty Acid Oxidation Disorders	nan	COMPLETED
Systemic Biomarkers of Brain Injury From Hyperammonemia	nan	RECRUITING
Effects of Parenteral L-carnitine Supplementation in Premature Neonates	nan	COMPLETED
Metabolic Effects of Medium-Chain Fatty Acids in Patients With Medium-Chain Acyl-CoA Dehydrogenase Deficiency and Healthy Individuals	nan	RECRUITING
Compassionate Use of Triheptanoin (C7) for Inherited Disorders of Energy Metabolism	nan	NO_LONGER_AVAILABLE
Study of Protein Translocation in Patients With Beta-Oxidation Disorders	nan	COMPLETED
GDF-15 as a Biomarker for Mitochondrial Disease	nan	COMPLETED
Nutritional Therapy of the Deficits of Oxidation Mitochondrial of the Fatty Acids	nan	COMPLETED
Exercise Intolerance Study in Long Chain Fatty Acid Oxidation Disorders	nan	RECRUITING
Lifestyle Intervention in Preparation for Pregnancy (LIPP)	nan	COMPLETED
Fatty Acid Metabolism and Insulin Sensitivity: the Role of Endurance Exercise	nan	COMPLETED
Cold Stress Stimulate the Browing of Subcutaneous White Adipose in Healthy Adults	nan	COMPLETED
Ketogenic Dietary Interventions in Autosomal Dominant Polycystic Kidney Disease (ADPKD)	nan	COMPLETED
Long-Chain Fatty Acid Oxidation Disorders In-Clinic Disease Monitoring Program	nan	ACTIVE_NOT_RECRUITING
Longitudinal Study of Mitochondrial Hepatopathies	nan	SUSPENDED
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
The LD Lync Study - Natural History Study of Lipodystrophy Syndromes	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a ACAD10 binder may also engage these)

Protein	Name	Similarity
Q8K370	—	1.000	Q8K370 →
Q8RWZ3	—	0.996	Q8RWZ3 →
Q80XL6	—	0.994	Q80XL6 →
Q5ZHT1	—	0.991	Q5ZHT1 →
Q5R778	—	0.990	Q5R778 →
B3DMA2	—	0.988	B3DMA2 →
Q5R5M8	—	0.988	Q5R5M8 →
Q8K009	—	0.987	Q8K009 →
EPHX2	Bifunctional epoxide hydrolase 2	0.987	landscape →
Q2QMG2	—	0.986	Q2QMG2 →
P80299	—	0.985	P80299 →
C5G8R4	—	0.985	C5G8R4 →
Q9XT75	—	0.985	Q9XT75 →
Q9JLH6	—	0.985	Q9JLH6 →
Q91YL3	—	0.985	Q91YL3 →
Q9NWZ5	—	0.985	Q9NWZ5 →
ALDH18A1	Delta-1-pyrroline-5-carboxylate synthase	0.985	landscape →
P39867	—	0.984	P39867 →
Q5R6G3	—	0.984	Q5R6G3 →
Q924N5	—	0.984	Q924N5 →
Q96SZ6	—	0.984	Q96SZ6 →
A7YWE4	—	0.983	A7YWE4 →
Q8BTW8	—	0.983	Q8BTW8 →
P51660	—	0.983	P51660 →
CBS	Cystathionine beta-synthase	0.983	landscape →
Q8W0Z7	—	0.983	Q8W0Z7 →
A0FKE6	—	0.983	A0FKE6 →
ACAD11	Acyl-CoA dehydrogenase family member 11	0.983	landscape →
Q5R557	—	0.983	Q5R557 →
A0A0U3BRC5	—	0.983	A0A0U3BRC5 →