Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5965815 | 1.00 | ARG1 (0.36) | ARG1ARG2GRM4MAPTHPGD | |
| SCHEMBL969629 | 0.87 | GRM4 (0.36) | GRM4 | |
| Trolamine SCHEMBL28825126 | 0.86 | ARG1 (0.34) | ARG1ARG2GRM4MAPTHPGD | |
| Trolamine SCHEMBL4518758 | 0.84 | MAPT (0.36) | ARG1ARG2MAPTHPGDMAPK1 | |
| Trolamine SCHEMBL28164611 | 0.79 | MAPT (0.36) | ARG1ARG2MAPTHPGDMAPK1 | |
| SCHEMBL8949497 | 0.79 | MAPT (0.36) | ARG1ARG2MAPTHPGDMAPK1 | |
| SCHEMBL2509365 | 0.78 | GRM4 (0.38) | ARG1ARG2GRM4MAPT | |
| SCHEMBL24818046 | 0.77 | LCK (0.33) | GRM4 | |
| SCHEMBL7103711 | 0.77 | MAPT (0.35) | ARG1ARG2MAPTHPGDMAPK1 | |
| SCHEMBL21909842 | 0.77 | DRD2 (0.32) | GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7427648-B2 | Hydrophilic siloxane copolymers and process for the preparation thereof | WACKER CHEMIE AG (DE) | 2008-09-23 | — | — | US | disclosed |
| US-20050272862-A1 | Hydrophilic siloxane copolymers and process for the preparation thereof | WACKER-CHEMIE GMBH (DE) | 2005-12-08 | — | — | US | disclosed |