Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3422912 | 1.00 | LMNA (0.50) | LMNADNM1CA12CA1CA2 | |
| SCHEMBL15861710 | 1.00 | LMNA (0.50) | LMNADNM1CA12CA1CA2 | |
| SCHEMBL183936 | 0.97 | LMNA (0.46) | LMNADNM1CA12CA1CA2 | |
| SCHEMBL1050623 | 0.88 | — | — | |
| SCHEMBL27885636 | 0.86 | LMNA (0.42) | LMNADNM1CA12CA1CA2 | |
| SCHEMBL20639323 | 0.86 | LMNA (0.48) | LMNADNM1CA12CA1CA2 | |
| SCHEMBL17062955 | 0.85 | ALDH1A1 (0.60) | LMNADNM1TSHRBLMCPB2 | |
| SCHEMBL17062963 | 0.84 | LMNA (0.64) | LMNADNM1TSHRBLMCPB2 | |
| SCHEMBL31526867 | 0.82 | LMNA (0.48) | LMNADNM1CA12CA1CA2 | |
| SCHEMBL8061903 | 0.82 | ALDH1A1 (0.62) | LMNADNM1TSHRGSRCPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390780-B2 | Gene delivery mediated by liposome-DNA complex with cleavable peg surface modification | ALZA CORPORATION (US) | 2008-06-24 | — | — | US | claimed |