SCHEMBL183936

SCHEMBL183936

NCCCCC(CO)CO

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
GSR P00390 1/20 0.42
NFKB1 P19838 2/20 0.41
RNPEP Q9H4A4 1/20 0.41
ALDH1A1 P00352 2/20 0.40
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA3 P07451 2/20 0.39
CA4 P22748 2/20 0.39
CA6 P23280 2/20 0.39
CA5A P35218 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
CA14 Q9ULX7 2/20 0.39
CA5B Q9Y2D0 2/20 0.39
TSHR P16473 2/20 0.39
DNM1 Q05193 1/20 0.39
BLM P54132 1/20 0.39
CPB2 Q96IY4 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3422912 0.97 LMNA (0.50) LMNAGSRNFKB1RNPEPALDH1A1
SCHEMBL15861710 0.97 LMNA (0.50) LMNAGSRNFKB1RNPEPALDH1A1
SCHEMBL5015299 0.97 LMNA (0.50) LMNAGSRNFKB1RNPEPALDH1A1
SCHEMBL1050623 0.91
SCHEMBL20639323 0.89 LMNA (0.48) LMNAGSRNFKB1RNPEPALDH1A1
SCHEMBL31526867 0.85 LMNA (0.48) LMNAGSRNFKB1RNPEPALDH1A1
SCHEMBL8061903 0.85 ALDH1A1 (0.62) LMNAGSRRNPEPALDH1A1TSHR
SCHEMBL23048319 0.83 LMNA (0.67) LMNAALDH1A1TSHRDNM1BLM
SCHEMBL17062955 0.83 ALDH1A1 (0.60) LMNAALDH1A1TSHRDNM1BLM
SCHEMBL14136512 0.83 LMNA (0.60) LMNAALDH1A1TSHRDNM1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121363052-B Ageing-resistant polyethylene-based dyed fiber and preparation method thereof GUANGDONG BIEM.L.FDLKK GOLF GARMENT Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-119236980-A VPO catalyst and application thereof in maleic anhydride preparation by n-butane oxidation 万华化学集团股份有限公司 2025-01-03 CN claimed
CN-118127663-A Method for preparing flame-retardant DTY polyester yarns by regenerating polyester fibers 安徽保尔盈新材料科技有限公司 2024-06-04 CN claimed
CN-117534765-A CD 28-targeting trispecific antibody construction method 北京大学深圳研究生院 2024-02-09 CN claimed
CN-113861403-A Nano material and preparation method and application thereof 北京化工大学 2021-12-31 CN claimed
US-20200016264-A1 NUCLEIC ACID OF FORMULA (I): GlXmGn, OR (II): ClXmCn, IN PARTICULAR AS AN IMMUNE-STIMULATING AGENT/ADJUVANT CUREVAC AG (DE) 2020-01-16 US claimed
US-10441653-B2 Nucleic acid comprising GlXmGn as an immune-stimulating agent/adjuvant CUREVAC AG (DE) 2019-10-15 US claimed
EP-3270949-A2 INSULIN ANALOGUES CONTAINING A GLUCOSE-REGULATED CONFORMATIONAL SWITCH Case Western Reserve University (US) 2018-01-24 EP claimed
WO-2016149222-A2 INSULIN ANALOGUES CONTAINING A GLUCOSE-REGULATED CONFORMATIONAL SWITCH CASE WESTERN RESERVE UNIVERSITY (US) 2016-09-22 WO claimed
CN-101874112-B Formula (I) especially as immunostimulant/adjuvant: GlXmGn or formula (II): the nucleic acid of ClXmCn 库瑞瓦格股份公司 2016-08-24 CN claimed
EP-1628531-A2 SYNERGISTIC TREATMENT OF CANCER USING IMMUNOMERS IN CONJUNCTION WITH CHEMOTHERAPEUTIC AGENTS HYBRIDON, INC. (US) 2006-03-01 EP claimed
US-20050026858-A1 Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes IDERA PHARMACEUTICALS, INC 2005-02-03 US claimed
US-20050009773-A1 Using oligonucleotide immunostimulant mixture with drug HYBRIDON, INC. 2005-01-13 US claimed
US-20040266710-A1 Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes IDERA PHARMACEUTICALS, INC 2004-12-30 US claimed
WO-2004103301-A2 SYNERGISTIC TREATMENT OF CANCER USING IMMUNOMERS IN CONJUNCTION WITH CHEMOTHERAPEUTIC AGENTS HYBRIDON, INC. (US) 2004-12-02 WO claimed
US-20040198685-A1 Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides HYBRIDON, INC. 2004-10-07 US claimed
US-20040136948-A1 Branched immunomodulatory compounds and methods of using the same DYNAVAX TECHNOLOGIES CORPORATION 2004-07-15 US claimed
US-20040097719-A1 Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends HYBRIDON, INC. 2004-05-20 US claimed
EP-1393745-A1 Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5'ends HYBRIDON, INC. (US) 2004-03-03 EP claimed
US-20020137714-A1 Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes IDERA PHARMACEUTICALS, INC 2002-09-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050009773-A1 Using oligonucleotide immunostimulant mixture with drug TLR3, TLR9, CD47 LMNA 4781/4885GSR 1444/4885NFKB1 256/4885
US-20040136948-A1 Branched immunomodulatory compounds and methods of using the same IFNG, ICOS, IL2 LMNA 4303/4885GSR 1674/4885NFKB1 378/4885
US-20020137714-A1 Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes STING1, IRF3, TLR9 LMNA 4812/4885GSR 1754/4885NFKB1 336/4885
US-20040198685-A1 Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides NT5C2, ENTPD5, TLR5 LMNA 4834/4885GSR 1664/4885NFKB1 538/4885
US-20040266710-A1 Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes STING1, IRF3, TLR9 LMNA 4812/4885GSR 1754/4885NFKB1 336/4885
US-20040097719-A1 Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends TLR5, TLR3, ENTPD5 LMNA 4649/4885GSR 3334/4885NFKB1 369/4885
US-20200016264-A1 NUCLEIC ACID OF FORMULA (I): GlXmGn, OR (II): ClXmCn, IN PARTICULAR AS AN IMMUNE-STIMULATING AGENT/ADJUVANT TLR9, TLR3, TLR5 LMNA 479/4885GSR 529/4885NFKB1 498/4885
US-20050026858-A1 Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes STING1, IRF3, TLR9 LMNA 4812/4885GSR 1754/4885NFKB1 336/4885
US-10441653-B2 Nucleic acid comprising GlXmGn as an immune-stimulating agent/adjuvant TLR9, TLR7, GMNN LMNA 1341/4885GSR 299/4885NFKB1 512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.