Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.31 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014107 | 0.85 | TSHR (0.35) | ELANEALDH1A1TSHRTHRB | |
| SCHEMBL3138262 | 0.81 | ACACB (0.36) | ALDH1A1TSHRTHRB | |
| SCHEMBL3128707 | 0.80 | TSHR (0.32) | TSHRTHRB | |
| SCHEMBL10427438 | 0.72 | TSHR (0.41) | ALDH1A1TSHRTHRB | |
| SCHEMBL22555500 | 0.71 | CASP1 (0.40) | CASP1ELANEALDH1A1MAPTNPC1 | |
| SCHEMBL1695697 | 0.71 | TSHR (0.44) | ALDH1A1TSHRTHRB | |
| SCHEMBL5015462 | 0.69 | TSHR (0.36) | ELANEALDH1A1MAPTTSHRHPGD | |
| SCHEMBL21768706 | 0.68 | HPGD (0.46) | ELANEALDH1A1MAPTCYP3A4HPGD | |
| SCHEMBL28119927 | 0.68 | TSHR (0.37) | ALDH1A1TSHRTHRB | |
| SCHEMBL1372183 | 0.68 | HPGD (0.42) | ELANEALDH1A1MAPTCYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200582-A1 | High refractive index monomers, compositions and uses thereof | CIBA CORP. | 2008-08-21 | — | — | US | disclosed |