Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.36 |
| ▸ | ACACA | Q13085 | 5/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014107 | 0.95 | TSHR (0.35) | ACACBACACAPTGS2TSHRTHRB | |
| SCHEMBL5015459 | 0.81 | CASP1 (0.38) | TSHRTHRBALDH1A1 | |
| SCHEMBL3128707 | 0.80 | TSHR (0.32) | TSHRTHRB | |
| SCHEMBL8615388 | 0.72 | PTGS2 (0.49) | ACACBACACAPTGS2 | |
| SCHEMBL10427438 | 0.72 | TSHR (0.41) | TSHRTHRBALDH1A1 | |
| SCHEMBL3138274 | 0.71 | EPHX1 (0.38) | ACACBACACATSHRALDH1A1 | |
| SCHEMBL1695697 | 0.71 | TSHR (0.44) | TSHRTHRBALDH1A1 | |
| SCHEMBL9971656 | 0.71 | ELANE (0.44) | ACACBACACAPTGS2TSHRALDH1A1 | |
| SCHEMBL7563914 | 0.69 | PTGS2 (0.47) | ACACBACACAPTGS2TSHRTHRB | |
| SCHEMBL14258939 | 0.69 | TSHR (0.41) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139878-A2 | HIGH REFRACTIVE INDEX MONOMERS, COMPOSITIONS AND USES THEREOF | BASF SE (DE) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008101806-A2 | HIGH REFRACTIVE INDEX MONOMERS, COMPOSITIONS AND USES THEREOF | BASF SE (CH) | 2008-08-28 | — | — | WO | disclosed |
| US-20080200582-A1 | High refractive index monomers, compositions and uses thereof | CIBA CORP. | 2008-08-21 | — | — | US | disclosed |