Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PDE6D | O43924 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5488110 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2PPARGPPARAPPARDMAPT | |
| SCHEMBL5015518 | 0.88 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL5017679 | 0.88 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL5015073 | 0.88 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL14010682 | 0.86 | PPARG (0.56) | PPARGPPARAPPARDMAPT | |
| SCHEMBL5015569 | 0.85 | PPARA (0.55) | PPARGPPARAPPARD | |
| SCHEMBL5023587 | 0.82 | PPARG (0.50) | PPARGPPARAPPARD | |
| SCHEMBL5015605 | 0.81 | PPARG (0.65) | PPARGPPARAPPARD | |
| SCHEMBL5015070 | 0.78 | PPARA (0.54) | PPARGPPARAPPARD | |
| SCHEMBL5014125 | 0.78 | PPARG (0.58) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869004-A1 | SUBSTITUTED CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES AND LIPID DISORDERS, THEIR PREPARATION AND USE | SK Holdings Co., Ltd. (KR) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006104349-A1 | SUBSTITUTED CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES AND LIPID DISORDERS, THEIR PREPARATION AND USE | SK HOLDINGS CO., LTD. (KR) | 2006-10-05 | — | — | WO | disclosed |