SCHEMBL5015572

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5015549	0.90	KDR (0.51)	KDRPDGFRBEGFRFGFR1FLT1
	SCHEMBL5025614	0.86	KDR (0.54)	KDRPDGFRBEGFRFGFR1FLT1
	SCHEMBL5025618	0.86	KDR (0.54)	KDRPDGFRBEGFRFGFR1FLT1
	SCHEMBL7129696	0.85	KDR (0.47)	KDRPDGFRBEGFRFGFR1FLT1
	SCHEMBL1401640	0.85	KDR (0.65)	KDRPDGFRBEGFRFGFR1FLT1
	SCHEMBL13998242	0.84	EGFR (0.42)	KDREGFRFGFR1FLT1FLT4
	SCHEMBL5017592	0.84	KDR (0.47)	KDRPDGFRBEGFRFGFR1FLT1
	SCHEMBL4451546	0.83	KDR (0.73)	KDRPDGFRBEGFRFGFR1FLT1
	SCHEMBL5015530	0.82	EGFR (0.42)	KDREGFRFGFR1FLT1FLT4
	SCHEMBL13998322	0.82	KDR (0.54)	KDRPDGFRBEGFRFGFR1FLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.